CAJ | 학술논문

目的探讨超声双重造影在进展期胃癌化疗疗效评价中的应用价值.方法对21例不能手术切除并接受化疗的进展期胃痛患者,在化疗前、后行口服胃窗造影及静脉超声造影(即超声双重造影)检查,并将化疗前、后超声造影结果进行比较.结果与化疗前比较,化疗后病灶厚度稍变薄,但差异无统计学意义(P＞0.05),化疗后胃癌组织的基础强度(BI)、峰值强度(PI)、造影剂到达时间(AT)及达峰时间(TTP)差异均无统计学意义(P＞0.05).而化疗后胃癌组织增强强度(EI)值明显降低,与化疗前比较差异具有统计学意义(P＜0.05).结论胃癌组织EI值可作为评价进展期胃癌化疗疗效的一项敏感、有效指标.
목적 탐토초성쌍중조영재진전기위암화료료효평개중적응용개치.방법 대21례불능수술절제병접수화료적진전기위통환자,재화료전、후행구복위창조영급정맥초성조영(즉초성쌍중조영)검사,병장화료전、후초성조영결과진행비교.결과 여화료전비교,화료후병조후도초변박,단차이무통계학의의(P＞0.05),화료후위암조직적기출강도(BI)、봉치강도(PI)、조영제도체시간(AT)급체봉시간(TTP)차이균무통계학의의(P＞0.05).이화료후위암조직증강강도(EI)치명현강저,여화료전비교차이구유통계학의의(P＜0.05).결론 위암조직EI치가작위평개진전기위암화료료효적일항민감、유효지표.
Objective To explore the clinical value of double contrast-enhanced ultrasonography (DCUS) on evaluation of the chemotherapy effect in advanced gastric carcinoma. Methods A total of 21 patients with unresectable and received chemotherapy of advanced gastric carcinoma were examined using ultrasound after taking oral contrast agent and bolus injection of Sono Vue, and findings of DCUS of each patient before and after chemotherapy were compared. Results The thickness of lesions was slightly thinner than that after chemotherapy,but there was no significant difference ( P ＞0. 05). In addition, there was no significant difference in the basal intensity (BI), peak intensity (PI), arrive time (AT) and time to peak (TTP) of gastric carcinoma tissues after chemotherapy (P ＞0.05). While the enhanced intensity (EI) value of gastric carcinoma tissues after chemotherapy was significantly less than that before chemotherapy (P ＜0.05). Conclusions The EI value in gastric carcinoma tissues may be considered as a sensitive and effective index in assessing the therapeutic effect of the chemotherapy in patients with advanced gastric carcinoma.