CAJ | 학술논문

目的通过运动单位数目估计技术检测糖尿病感觉神经病患者运动单位,以期评估其下运动神经功能状态.方法纳入54例符合世界卫生组织糖尿病周围神经病国际协作研究诊断标准的糖尿病周围神经病(DPN)住院患者,并根据尺神经传导异常结果分组:感觉异常组(即仅有感觉传导异常而运动传导正常)33例,其中男20例,女13例;感觉运动异常组(即感觉传导和运动传导均异常)21例,其中男13例,女8例,并与42名健康人对照.应用Keypoint4肌电诱发电位仪,计数各组小鱼际肌运动单位数目,同时记录54例DPN患者入院后糖尿病病程和空腹血糖.结果感觉异常组、感觉运动异常组和健康对照组的小鱼际肌运动单位数目分别为97.1±47.6、63.3±22.3、173.0±75.5(F=21.259,P=0.000);54例DPN患者小鱼际肌运动单位数目(84.0±42.8)与糖尿病病程(1个月至26年)呈负相关(r=0.414,P=0.002),与空腹血糖水平(5.0～20.4 mmol/L)无明显相关.结论糖尿病感觉神经病存在着临床下运动神经损害,运动单位的丢失程度受糖尿病病程的影响.
목적 통과운동단위수목고계기술검측당뇨병감각신경병환자운동단위,이기평고기하운동신경공능상태.방법 납입54례부합세계위생조직당뇨병주위신경병국제협작연구진단표준적당뇨병주위신경병(DPN)주원환자,병근거척신경전도이상결과분조:감각이상조(즉부유감각전도이상이운동전도정상)33례,기중남20례,녀13례;감각운동이상조(즉감각전도화운동전도균이상)21례,기중남13례,녀8례,병여42명건강인대조.응용Keypoint4기전유발전위의,계수각조소어제기운동단위수목,동시기록54례DPN환자입원후당뇨병병정화공복혈당.결과 감각이상조、감각운동이상조화건강대조조적소어제기운동단위수목분별위97.1±47.6、63.3±22.3、173.0±75.5(F=21.259,P=0.000);54례DPN환자소어제기운동단위수목(84.0±42.8)여당뇨병병정(1개월지26년)정부상관(r=0.414,P=0.002),여공복혈당수평(5.0～20.4 mmol/L)무명현상관.결론 당뇨병감각신경병존재착림상하운동신경손해,운동단위적주실정도수당뇨병병정적영향.
Objective To evaluate the function of motor nerve in patients with diabetic sensory neuropathy (DPN) by estimating the motor units.Methods Fifty-four patients with DPN were divided into two groups according to the nerve conduction abnormality of ulnar nerve.The paresthosia group only included patients of 33 patients (20 male, 13 female) with abnormal sensory conduction.The admixture group included 21 patients (13 male, 8 female) with abnormal motor sensory conduction.The control group included 42 healthy people.A Keypoint4 electromyogram device was used to estimate the motor units of hypothenar muscle, and the fasting blood glucose and the duration of diabetes mellitus were documented.Results The motor units of hypothenar muscle in paresthesia group, admixture group and control group was 97.1±47.6, 63.3±22.3, 173.0±75.5 (F=21.259, P=0.000) respectively.The hypothcnar muscle motor units(84.0±42.8) in 54 patients with DPN had negative correlation (r=-0.414, P=0.002) with the duration of diabetes mellitus (1 month to 26 years) and had no evident correlation with fasting blood glucose (5.0-20.4 mmol/L).Conclusion There is clinical motor nerve damage in patients with diabetic sensory neuropathy, and the loss of motor units is impacted by the duration of diabetes mellitus.