应用数学和力学(英文版)
應用數學和力學(英文版)
응용수학화역학(영문판)
APPLIED MATHEMATICS AND MECHANICS(ENGLISH EDITION)
2004年
4期
440-444
,共5页
刘宇红%曾衍钧%许景锋%张梅
劉宇紅%曾衍鈞%許景鋒%張梅
류우홍%증연균%허경봉%장매
nonlinear regression model%penetration coefficient%transdermal drug delivery system (TDDS)
Transdermal drug delivery system (TDDS) is a new method for drug delivery. The analysis of plenty of experiments in vitro can lead to a suitable mathematical model for the description of the process of the drug's penetration through the skin, together with the important parameters that are related to the characters of the drugs.After the research work of the experiments data,a suitable nonlinear regression model was selected. Using this model, the most important parameter-penetrated coefficient of 20 drugs was computed.In the result one can find, this work supports the theory that the skin can be regarded as singular membrane.
