国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2012年
10期
896-897
,共2页
治泻方%小肠运动与吸收
治瀉方%小腸運動與吸收
치사방%소장운동여흡수
Zhixie recipe%Small intestinal motion and absorption
目的 通过本实验,观察治泻方对小鼠小肠运动功能及对兔小肠吸收功能的影响,探讨治泻方的药效机理.方法 用治泻方药液灌喂小鼠,以蒸馏水灌喂作为对照,然后各组灌喂印度墨汁,处死小鼠后记录墨汁在小肠移动的长度;将治泻方药液与台式液混合,分别配制成浓度为5％泻台液、10％泻台液,并以台式液作为对照液,将这三组药液分别注入兔小肠,然后抽出各段肠液进行氯离子测定.结果 在体小肠运动实验中A、B、C三组小鼠墨汁移动的平均百分率分别为52.55％ (SD=8.24)、54.35％(SD=12.53)、59.45％ (SD=14.17),其中A组、B组分别与C组比较,差异均无统计学意义(P＞0.05);在小肠吸收功能实验中5％、10％泻台液与台式液比较,差异均有统计学意义(x2值分别为6.92、46.18,P＜0.01),表明5％、10％泻台液均可促进小肠对氯离子的吸收,其中10％泻台液作用更佳.结论 治泻方不影响小鼠在体肠管的运动功能并能促进兔小肠吸收功能.
目的 通過本實驗,觀察治瀉方對小鼠小腸運動功能及對兔小腸吸收功能的影響,探討治瀉方的藥效機理.方法 用治瀉方藥液灌餵小鼠,以蒸餾水灌餵作為對照,然後各組灌餵印度墨汁,處死小鼠後記錄墨汁在小腸移動的長度;將治瀉方藥液與檯式液混閤,分彆配製成濃度為5％瀉檯液、10％瀉檯液,併以檯式液作為對照液,將這三組藥液分彆註入兔小腸,然後抽齣各段腸液進行氯離子測定.結果 在體小腸運動實驗中A、B、C三組小鼠墨汁移動的平均百分率分彆為52.55％ (SD=8.24)、54.35％(SD=12.53)、59.45％ (SD=14.17),其中A組、B組分彆與C組比較,差異均無統計學意義(P＞0.05);在小腸吸收功能實驗中5％、10％瀉檯液與檯式液比較,差異均有統計學意義(x2值分彆為6.92、46.18,P＜0.01),錶明5％、10％瀉檯液均可促進小腸對氯離子的吸收,其中10％瀉檯液作用更佳.結論 治瀉方不影響小鼠在體腸管的運動功能併能促進兔小腸吸收功能.
목적 통과본실험,관찰치사방대소서소장운동공능급대토소장흡수공능적영향,탐토치사방적약효궤리.방법 용치사방약액관위소서,이증류수관위작위대조,연후각조관위인도묵즙,처사소서후기록묵즙재소장이동적장도;장치사방약액여태식액혼합,분별배제성농도위5％사태액、10％사태액,병이태식액작위대조액,장저삼조약액분별주입토소장,연후추출각단장액진행록리자측정.결과 재체소장운동실험중A、B、C삼조소서묵즙이동적평균백분솔분별위52.55％ (SD=8.24)、54.35％(SD=12.53)、59.45％ (SD=14.17),기중A조、B조분별여C조비교,차이균무통계학의의(P＞0.05);재소장흡수공능실험중5％、10％사태액여태식액비교,차이균유통계학의의(x2치분별위6.92、46.18,P＜0.01),표명5％、10％사태액균가촉진소장대록리자적흡수,기중10％사태액작용경가.결론 치사방불영향소서재체장관적운동공능병능촉진토소장흡수공능.
Objective To investigate the effects and mechanism of Zhixie recipe on small intestinal motility of rats and absorption ability of rabbits.Methods Three groups of rats,one was fed with distilled water,the another two were fed with Zhixie recipe liquid of 1 g/ml and 2 g/ml.Then all three groups were fed with ink,and the moving distance of the ink in small intestines was measured to check the small intestinal motility; Three mixtures of Zhixie recipe liquid and desktop solution with 0％,5％ and 10％ Zhixie recipe liquid were injected into rabbits,the Chloride ion concentration in small intestines was measured to check the absorption ability.Results The average moving distance percentage of ink in the small intestines of the three groups of rats was 52.55％ ( SD =8.24),54.35％ (SD =12.53 ) and 59.45％ ( SD=14.17) of the total intestine length respectively.It showed that Zhixie recipe had no influence on small intestinal motility (P＞0.05) ; Small intestines absorption experiments revealed that the small intestinal absorption ability was quite different between the rabbits with desktop solution and the rabbits with mixtures of Zhixie recipe liquid and Desktop solution (5％ and 10％),with x2=6.92 and 46.18,P＜0.01.The mixtures with 5％ and 10％ Zhixie recipe liquid improved the small intestinal absorption ability,and the effect of the mixture with 10％ was even stronger.Conclusion Zhixie recipe showed no influence on small intestinal motility,but it improved the small intestinal absorption ability.
