中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2010年
10期
903-907
,共5页
孕妇%糖尿病%体重增长%营养疗法
孕婦%糖尿病%體重增長%營養療法
잉부%당뇨병%체중증장%영양요법
Pregnant women%Diabetes mellitus%Weight gain%Nutrition therapy
目的 探讨孕期体重增长情况与妊娠期糖尿病(GDM)的关系,分析饮食治疗对改善GDM结局的作用.方法 2007-2009年,在厦门市妇幼保健院收集GDM患者265例,并以同期就诊的正常孕妇571名作为对照组.收集一般情况资料并于孕20周前、孕26~27周(孕中期)、孕35~36周(孕晚期)及分娩前监测体重,分析不同年龄段(<25、25~、30~、≥35岁)两组孕妇不同孕周的体重增长情况及28周前体重增长对GDM发病的影响,同时对GDM患者给予营养治疗并评价血糖控制情况对妊娠结局的影响.结果 25~、30~、≥35岁年龄段GDM组孕期总体重增长分别为(16.9±6.3)、(16.8±6.1)、(16.5±6.0)kg,对照组分别为(13.9±3.0)、(13.8±2.7)、(13.3±2.7)kg(t值分别为6.259、5.885、3.533,P值均<0.05);孕20~27周间,<25、25~、30~岁年龄段GDM组增长的体重分别为(5.2±1.0)、(5.4±1.7)、(4.8±1.3)kg,对照组分别为(3.3±1.3)、(3.7±1.6)、(3.5±0.7)kg(t值分别为5.026、9.659、11.19,P值均<0.05);孕26~36周间,≥35岁年龄段GDM组体重增长为(3.6±2.0)kg,低于对照组的(4.0±0.9)kg(t=-2.449,P<0.05).25~、30~岁年龄段GDM组孕28周前体重增长超过13 kg的暴露率分别为41.22%(54/131)及44.94%(40/89),对照组分别为30.04%(76/253)及26.07%(55/211)(OR值分别为1.633、2.315,P值均<0.05).血糖控制良好组及对照组的新生儿出生体重异常率分别为6.6%(12/182)及9.4%(54/571),均低于血糖控制不佳组的20.5%(17/83)(x2值分别为11.490、9.119,P值均<0.0125),血糖控制不佳组早产率为21.7%(18/83),高于对照组的10.8%(62/571)(x2=7.945,P<0.0125).血糖控制良好组及血糖控制不佳组的剖宫产率分别为46.7%(85/182)及65.0%(54/83),均高于对照组的25.4%(145/571)(x2值分别为29.540、53.860,P值均<0.0125).结论 孕中期体重增长对GDM的发病有影响,25~岁年龄段的孕妇孕28周前总体重增长不宜超过13 kg;及时对GDM孕妇进行营养治疗并控制血糖,能改善其妊娠结局.
目的 探討孕期體重增長情況與妊娠期糖尿病(GDM)的關繫,分析飲食治療對改善GDM結跼的作用.方法 2007-2009年,在廈門市婦幼保健院收集GDM患者265例,併以同期就診的正常孕婦571名作為對照組.收集一般情況資料併于孕20週前、孕26~27週(孕中期)、孕35~36週(孕晚期)及分娩前鑑測體重,分析不同年齡段(<25、25~、30~、≥35歲)兩組孕婦不同孕週的體重增長情況及28週前體重增長對GDM髮病的影響,同時對GDM患者給予營養治療併評價血糖控製情況對妊娠結跼的影響.結果 25~、30~、≥35歲年齡段GDM組孕期總體重增長分彆為(16.9±6.3)、(16.8±6.1)、(16.5±6.0)kg,對照組分彆為(13.9±3.0)、(13.8±2.7)、(13.3±2.7)kg(t值分彆為6.259、5.885、3.533,P值均<0.05);孕20~27週間,<25、25~、30~歲年齡段GDM組增長的體重分彆為(5.2±1.0)、(5.4±1.7)、(4.8±1.3)kg,對照組分彆為(3.3±1.3)、(3.7±1.6)、(3.5±0.7)kg(t值分彆為5.026、9.659、11.19,P值均<0.05);孕26~36週間,≥35歲年齡段GDM組體重增長為(3.6±2.0)kg,低于對照組的(4.0±0.9)kg(t=-2.449,P<0.05).25~、30~歲年齡段GDM組孕28週前體重增長超過13 kg的暴露率分彆為41.22%(54/131)及44.94%(40/89),對照組分彆為30.04%(76/253)及26.07%(55/211)(OR值分彆為1.633、2.315,P值均<0.05).血糖控製良好組及對照組的新生兒齣生體重異常率分彆為6.6%(12/182)及9.4%(54/571),均低于血糖控製不佳組的20.5%(17/83)(x2值分彆為11.490、9.119,P值均<0.0125),血糖控製不佳組早產率為21.7%(18/83),高于對照組的10.8%(62/571)(x2=7.945,P<0.0125).血糖控製良好組及血糖控製不佳組的剖宮產率分彆為46.7%(85/182)及65.0%(54/83),均高于對照組的25.4%(145/571)(x2值分彆為29.540、53.860,P值均<0.0125).結論 孕中期體重增長對GDM的髮病有影響,25~歲年齡段的孕婦孕28週前總體重增長不宜超過13 kg;及時對GDM孕婦進行營養治療併控製血糖,能改善其妊娠結跼.
목적 탐토잉기체중증장정황여임신기당뇨병(GDM)적관계,분석음식치료대개선GDM결국적작용.방법 2007-2009년,재하문시부유보건원수집GDM환자265례,병이동기취진적정상잉부571명작위대조조.수집일반정황자료병우잉20주전、잉26~27주(잉중기)、잉35~36주(잉만기)급분면전감측체중,분석불동년령단(<25、25~、30~、≥35세)량조잉부불동잉주적체중증장정황급28주전체중증장대GDM발병적영향,동시대GDM환자급여영양치료병평개혈당공제정황대임신결국적영향.결과 25~、30~、≥35세년령단GDM조잉기총체중증장분별위(16.9±6.3)、(16.8±6.1)、(16.5±6.0)kg,대조조분별위(13.9±3.0)、(13.8±2.7)、(13.3±2.7)kg(t치분별위6.259、5.885、3.533,P치균<0.05);잉20~27주간,<25、25~、30~세년령단GDM조증장적체중분별위(5.2±1.0)、(5.4±1.7)、(4.8±1.3)kg,대조조분별위(3.3±1.3)、(3.7±1.6)、(3.5±0.7)kg(t치분별위5.026、9.659、11.19,P치균<0.05);잉26~36주간,≥35세년령단GDM조체중증장위(3.6±2.0)kg,저우대조조적(4.0±0.9)kg(t=-2.449,P<0.05).25~、30~세년령단GDM조잉28주전체중증장초과13 kg적폭로솔분별위41.22%(54/131)급44.94%(40/89),대조조분별위30.04%(76/253)급26.07%(55/211)(OR치분별위1.633、2.315,P치균<0.05).혈당공제량호조급대조조적신생인출생체중이상솔분별위6.6%(12/182)급9.4%(54/571),균저우혈당공제불가조적20.5%(17/83)(x2치분별위11.490、9.119,P치균<0.0125),혈당공제불가조조산솔위21.7%(18/83),고우대조조적10.8%(62/571)(x2=7.945,P<0.0125).혈당공제량호조급혈당공제불가조적부궁산솔분별위46.7%(85/182)급65.0%(54/83),균고우대조조적25.4%(145/571)(x2치분별위29.540、53.860,P치균<0.0125).결론 잉중기체중증장대GDM적발병유영향,25~세년령단적잉부잉28주전총체중증장불의초과13 kg;급시대GDM잉부진행영양치료병공제혈당,능개선기임신결국.
Objective To study the relationship of bodyweight gain and the occurrence of gestational diabetes mellitus (GDM) during pregnancy, and analyze the effect of the nutritional therapy on the outcome of GDM. Methods We collected 265 pregnant women who were diagnosed to be GDM and 571 pregnant women as the control group in the Xiamen Maternal and Child Health Hospital during 2007 -2009. The general information of the subjects were collected. The bodyweight of the subjects were measured before the 20th week of pregnancy, 26 - 27th week ( mid-gestation ), 35 - 36th week ( late-gestation ) of pregnancy and prior to delivery. The bodyweight gain of different pregnancy weeks of the two groups and the effect of bodyweight on GMD occurrence before 28th week of pregnancy were analyzed by ages ( <25,25 -,30-, ≥35). Meanwhile,we prescribed the nutrition therapy to the GDM pregnant woman and the effect of the blood sugar control on the outcome of the pregnancy were evaluated. Results The bodyweight gain of 25 - ,30 - ,older than 35 year-old subjects of the GDM group were ( 16.9 ±6.3), ( 16.8 ±6.1 ), ( 16.5 ±6.0) kg,respectively, the bodyweight gain of the control group were ( 13.9 ± 3.0 ), ( 13.8 ± 2.7 ), ( 13.3 ±2.7 ) kg ( t = 6.259,5.885,3.533, respectively, all P values < 0.05 ). During the 20th to 27th week of the pregnancy,the bodyweight gain of the subjects younger than 25,25 -, 30 - year-old in GDM group were (5.2 ± 1.0), ( 5.4 ± 1.7 ), ( 4.8 ±1.3 ) kg, respectively, the bodyweight gain of the control group were (3.3±1.3),(3.7 ±1.6) and (3.5 ±0.7)kg (t=5.026,9.659,11.19,respectively,all P values<0.05 ). During the period between 26th to 36th week, the bodyweight gain of subjects older than 35 year-old in GDP group was ( 3.6 ± 2.0 ) kg which was less than the control group ( (4.0 ± 0.9 ) kg, t = - 2.449, P <0.05 ). 41.22% ( 54/131 ) and 44. 94% ( 40/89 ) of 25 - , 30 - year-old subjects in GDM group showed bodyweight gain more than 13 kg, but 30.04% ( 76/253 ) and 26.07% ( 55/211 ) in the control group ( OR values were 1.633 and 2.315, both P values < 0.05 ). The rate of the abnormal birth weight of the GDM group with blood sugar controlled and the control group were 6.6% ( 12/182 )and 9.4% (54/571 )which was lower than the GDP group with blood sugar control failure (20.5% (17/83)) (x2 values were 11.460,9.119,respectively, both P values < 0.0125 ). The rate of premature delivery was 21.7% (18/83), higher than the control group ( 10.8% ,62/571 ) ( x2 = 7.945, P < 0.0125 ). The rate of the cesarean in the control group was 25.4% ( 145/571 ) which was lower than the two GDM groups, including the group which the blood sugar was well controlled (46.7% ,85/182) and not well controlled (65.0% ,54/83 ) ( x2 values were 29.540,53.860,respectively, both P values < 0.0125 ). Conclusion The bodyweight gain in the midgestation could affect the occurrence of GDM. The bodyweight gain should be less than 13 kg before 28th week of the pregnancy whose age was 25 - year-old. Nutritional therapy and blood sugar control in GDM pregnant women could improve the pregnancy outcome.