CAJ | 학술논문

目的探讨声触诊组织定量(virtual touch tissue quantification,VTQ)技术在慢性移植肾肾病(chronic allograft nephropathy,CAN)检测中的应用价值.方法选择48例移植肾功能正常患者及50例CAN患者,分别对移植肾行彩色多普勒及VTQ检查,并对检查结果进行对比分析.结果 CAN组和移植肾功能正常组之间VTQ值差异有统计学意义(P＜0,05).用ROC曲线分析阈值,当VTQ值≥2.51 m/s时,诊断CAN的敏感性、特异性、阳性预测值、阴性预测值分别为76.0％、52.1％、60.3％、65.7％,诊断准确度为62.2％.结论 VTQ技术可定量反映移植肾皮质的弹性变化,测值稳定,可重复性强,能够用于监测移植肾功能变化及早期诊断CAN.
목적 탐토성촉진조직정량(virtual touch tissue quantification,VTQ)기술재만성이식신신병(chronic allograft nephropathy,CAN)검측중적응용개치.방법 선택48례이식신공능정상환자급50례CAN환자,분별대이식신행채색다보륵급VTQ검사,병대검사결과진행대비분석.결과 CAN조화이식신공능정상조지간VTQ치차이유통계학의의(P＜0,05).용ROC곡선분석역치,당VTQ치≥2.51 m/s시,진단CAN적민감성、특이성、양성예측치、음성예측치분별위76.0％、52.1％、60.3％、65.7％,진단준학도위62.2％.결론 VTQ기술가정량반영이식신피질적탄성변화,측치은정,가중복성강,능구용우감측이식신공능변화급조기진단CAN.
Objective To investigate the feasibility of virtual touch tissue quantification(VTQ) for the assessment of chronic allograft nephropathy(CAN).Methods 48 patients with normal renal function and 50 patients with CAN were checked by color Doppler and VTQ technique.All the results were compared　between two groups.Results Mean VTQ-values were significantly different between the two groups( P ＜ 0.05).ROC curve displayed that VTQ value of 2.51 m/s could be used to diagnose CAN,the sensitivity,specificity,positive predictive value and negative predictive value were 76.0％,52.1％,60.3％ and 65.7％,respectively.The diagnostic efficiency was 62.2％.Conclusions Parenchymal stiffness measured by VTQ is stable and repeatable,which can be used to diagnose patients with CAN and to monitor renal function.