CAJ | 학술논문

观察双环醇联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效。方法将80例非酒精性脂肪性肝炎患者，按数字表法随机分为治疗组(40例)及对照组(40例)。治疗组在控制饮食、适当运动基础上给予双环醇联合多烯磷脂酰胆碱治疗；对照组在控制饮食、适当运动基础上给予熊去氧胆酸治疗。全部病例均连续治疗12周。结果治疗组总有效率为85.0％(34/40)，对照组为55.0％(22/40)，两组差异有统计学意义(x2=8.5，P＜0.01)。治疗后，治疗组ALT、AST、TG、TC与对照组相比，差异有统计学意义(t=2.13、3.36、5.00、4.45，P＜0.05)。结论应用双环醇联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎有效，值得临床应用。
관찰쌍배순연합다희린지선담감치료비주정성지방성간염적료효。방법장80례비주정성지방성간염환자，안수자표법수궤분위치료조(40례)급대조조(40례)。치료조재공제음식、괄당운동기출상급여쌍배순연합다희린지선담감치료；대조조재공제음식、괄당운동기출상급여웅거양담산치료。전부병례균련속치료12주。결과치료조총유효솔위85.0％(34/40)，대조조위55.0％(22/40)，량조차이유통계학의의(x2=8.5，P＜0.01)。치료후，치료조ALT、AST、TG、TC여대조조상비，차이유통계학의의(t=2.13、3.36、5.00、4.45，P＜0.05)。결론응용쌍배순연합다희린지선담감치료비주정성지방성간염유효，치득림상응용。
Objective To observe the effects of bicyclol combined with polyunsaturated phosphatidylcholine in the treatment of non-alcoholic fatty hepatitis. Methods 80 patients with non-alcoholic steatohepatitis patients were randomly divided into treatment group (40 cases) and control group (40 cases). On the basis of diet control and adequate exercise, the treatment group was given united bicyclol polyene phosphatidylcholine and the control group was given ursodeoxycholic acid. All the patients were treated for 12 weeks. Results The total effective rate in treatment group was 85.0％(34/40), the rate was 55.0％ (22/40)in control group, and there was statistical difference between the two groups( x2 = 8.5, P ＜ 0.01 ). In treatment group, ALT, AST, TG, TC decreased significantly compared to those in control group(t=2.13, 3.36, 5.00, 4.45, P＜0.05).Conclusions Bicyclol combiined with polyunsaturated phosphatidylcholine for nonalcoholic steatohepatitis therapy is effective and worthy for clinical application.