CAJ | 학술논문

目的探讨母婴阻断治疗及护理对妊娠梅毒患者的影响.方法采用回顾性方法对住院分娩的108例妊娠梅毒患者及婴儿资料进行随访分析,比较治疗与非治疗患者妊娠结局及新生儿预后情况.结果 108例妊娠梅毒孕妇分娩孕周平均(38.22±1.795)周,早产5例占4.63％,治疗组足月产率98.51％高于未治疗组的90.24％,但差异无统计学意义(x2=2.29,P＞0.05)；治疗组孕妇分娩的先天梅毒患儿为4.48％少于未治疗组的29.27％,差异有统计学意义(x2=13.07,P＜0.01)；孕妇在孕期未行正规治疗或未治疗者,及新生儿诊为先天梅毒者,立即进行驱梅治疗,79.63％血浆反应素环状卡片试验(RPR)在1岁内全部转阴,79.41％梅毒螺旋体颗粒凝集试验(TPPA)在18个月内转阴,其余均为2-3年内转阴.结论加强妊娠梅毒孕妇的孕期保健和管理工作,做好宣传教育和婴儿的随访监测工作,对预防先天性梅毒及保证婴儿的健康成长有重要意义.
목적 탐토모영조단치료급호리대임신매독환자적영향.방법 채용회고성방법대주원분면적108례임신매독환자급영인자료진행수방분석,비교치료여비치료환자임신결국급신생인예후정황.결과 108례임신매독잉부분면잉주평균(38.22±1.795)주,조산5례점4.63％,치료조족월산솔98.51％고우미치료조적90.24％,단차이무통계학의의(x2=2.29,P＞0.05)；치료조잉부분면적선천매독환인위4.48％소우미치료조적29.27％,차이유통계학의의(x2=13.07,P＜0.01)；잉부재잉기미행정규치료혹미치료자,급신생인진위선천매독자,립즉진행구매치료,79.63％혈장반응소배상잡편시험(RPR)재1세내전부전음,79.41％매독라선체과립응집시험(TPPA)재18개월내전음,기여균위2-3년내전음.결론 가강임신매독잉부적잉기보건화관리공작,주호선전교육화영인적수방감측공작,대예방선천성매독급보증영인적건강성장유중요의의.
Objective To explore blocking of maternal-fetal transmission of syphilis in pregnancy and nursing care.Methods By retrospectively analyzing 108 cases,collected from January 2005 to October 2007,of blocking matemal-fetal transmission data among pregnant women infected with syphilis.Pregnancy outcome and prognosis status were compared between those under therapy and those were not. Results Average gestational week was( 38.22 ± 1.795 ) weeks,5 patients had premature delivery,accounting for 4.63％ ; Fullterm rate in treatment group was 98.51％ and 90.24％ in untreatment group,and the difference was not statistically significant ( x2 =2.29,P ＞ 0.05 ) ; Infants with congenital syphilis in treatment group was 4.48％ and less than 29.27％ in the untreatment group,and the difference was significant ( x2 =13.07,P ＜ 0.01 ) ;Those pregnant women,who did not receive standard treatment and the infant was diagnosed as congenital syphilis,were treated with anti-syphilitic therapy,and 79.63％ of RPR was negative within one year,79.41％ of TPPA was negative within 18 months,and all the other turned negative in 2 -3 years.Conclusions Reinforcing health care and supervision during gestation and evaluating pregnant women syphilis infection and treatment condition in time could prevent them from cross-infection and insure the healthy growth of children.