中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2010年
2期
143-145
,共3页
金景%江钟立%贺丹军%孟殿怀
金景%江鐘立%賀丹軍%孟殿懷
금경%강종립%하단군%맹전부
基底节区卒中%内隐学习%学习能力
基底節區卒中%內隱學習%學習能力
기저절구졸중%내은학습%학습능력
Basal ganglia stroke%Implicit learning%Learning potential
目的 探讨基底节区卒中患者内隐学习损害的特征以及受损的状况.方法 基底节区卒中患者17例,其中左侧基底节区卒中组8例,右侧基底节区卒中组9例.同期住院的非脑部疾病的患者或无任何疾病的健康者10例.采用天气预报分类学习任务(WPCLT)、威斯康星卡片分类(WCST)分别对左右侧基底节损伤患者和对照组进行连续3d的测试.结果 右侧基底节卒中组连续3d的WPCLT 总正确率和正常对照组相比均差异具有显著性[(52.72±5.57)%,(61.85±8.49)%,F=3.55,P=0.048:(55.83±4.52)%,(71.85±10.89)%,F=7.74,P=0.003;(62.33±7.70)%,(80.15±6.67)%,F=10.96,P=0.001],左侧基底节组在第3天的测试中WPCLT总正确率显著差于正常对照组(F=10.96,P=0.009).左右侧基底节卒中患者的WPCLT学习能力均明显低于正常对照组F=12.42,P<0.01).正常对照组在第2天的测试中WPCLT总分与WCST的完成分类数有显著相关,在第3天的测试中WPCLT总分与WCST的错误率和完成分类数有显著相关.结论 基底节区卒中的患者内隐学习受损,且内隐-外显的学习模式也受损.
目的 探討基底節區卒中患者內隱學習損害的特徵以及受損的狀況.方法 基底節區卒中患者17例,其中左側基底節區卒中組8例,右側基底節區卒中組9例.同期住院的非腦部疾病的患者或無任何疾病的健康者10例.採用天氣預報分類學習任務(WPCLT)、威斯康星卡片分類(WCST)分彆對左右側基底節損傷患者和對照組進行連續3d的測試.結果 右側基底節卒中組連續3d的WPCLT 總正確率和正常對照組相比均差異具有顯著性[(52.72±5.57)%,(61.85±8.49)%,F=3.55,P=0.048:(55.83±4.52)%,(71.85±10.89)%,F=7.74,P=0.003;(62.33±7.70)%,(80.15±6.67)%,F=10.96,P=0.001],左側基底節組在第3天的測試中WPCLT總正確率顯著差于正常對照組(F=10.96,P=0.009).左右側基底節卒中患者的WPCLT學習能力均明顯低于正常對照組F=12.42,P<0.01).正常對照組在第2天的測試中WPCLT總分與WCST的完成分類數有顯著相關,在第3天的測試中WPCLT總分與WCST的錯誤率和完成分類數有顯著相關.結論 基底節區卒中的患者內隱學習受損,且內隱-外顯的學習模式也受損.
목적 탐토기저절구졸중환자내은학습손해적특정이급수손적상황.방법 기저절구졸중환자17례,기중좌측기저절구졸중조8례,우측기저절구졸중조9례.동기주원적비뇌부질병적환자혹무임하질병적건강자10례.채용천기예보분류학습임무(WPCLT)、위사강성잡편분류(WCST)분별대좌우측기저절손상환자화대조조진행련속3d적측시.결과 우측기저절졸중조련속3d적WPCLT 총정학솔화정상대조조상비균차이구유현저성[(52.72±5.57)%,(61.85±8.49)%,F=3.55,P=0.048:(55.83±4.52)%,(71.85±10.89)%,F=7.74,P=0.003;(62.33±7.70)%,(80.15±6.67)%,F=10.96,P=0.001],좌측기저절조재제3천적측시중WPCLT총정학솔현저차우정상대조조(F=10.96,P=0.009).좌우측기저절졸중환자적WPCLT학습능력균명현저우정상대조조F=12.42,P<0.01).정상대조조재제2천적측시중WPCLT총분여WCST적완성분류수유현저상관,재제3천적측시중WPCLT총분여WCST적착오솔화완성분류수유현저상관.결론 기저절구졸중적환자내은학습수손,차내은-외현적학습모식야수손.
Objectives To gain a deeper understanding of the role of the basal ganglia in implicit learning by examining Weather Prediction Category Learning Task among patients with basal ganglia stroke.Methods Seventeen patients with basal ganglia stroke including eight cases of left basal ganglia lesions and nine cases of right basal ganglia lesions.Ten cases without brain damage were used as contr0l.All of the subjects were tested by use of Weather Prediction Category Learning Task(WPCLT) and Wisconsin Card Sorting Test (WCST)in 3 consecutive days.Results The patients with right basal ganglia lesions were consistently impaired compared with the controls((52.72±5.57)%vs(61.85±8.49)%,F=3.55,P=0.048);(55.83±4.52)%vs(71.85±10.89)%,F=7.74,P=0.003);(62.33±7.70)%vs(80.15±6.67)%,F=10.96,P=0.001)),and the patients with right basal ganglia lesions were impaired in the last day(F=10.96,P=0.009).But in patients of left and right basal ganglia lesions,the learning potential of WPCLT decreased significantly compared with the control(P<0.01).In the control group,the WPCLT total number of correct and WCST Number of Categories Completed were hishly related in the second day.The WPCLT total number of correct correlated significantly with Percent Errors and Number of Categories Completed of WCST in the third day.Conclusion The basal ganglia lesions may decrease implicit learning,and the bottom-up(implicit-to-explicit)learning pattern is impaired in patients with basal ganglia lesions.