CAJ | 학술논문

目的探讨石菖蒲挥发油包合工艺,并对其包合物稳定性进行研究.方法应用U7(7~6)均匀试验设计对影响包合的因素进行考察,筛选出最佳包合工艺;采用HPLC法,以β-细辛醚含量为指标研究包合前后石菖蒲挥发油稳定性.结果石菖蒲挥发油的最佳包合工艺为:β-CD:挥发油=3:1,β-CD:水=1:15,包合温度为30℃,搅拌时间为3 h;包合后,在考察时间范围内石菖蒲挥发油中β-细辛醚含量变化较小,RSD<5%.结论筛选出的包合工艺稳定可行,采用β-CD包合可有效提高石菖蒲挥发油的稳定性.
목적 탐토석창포휘발유포합공예,병대기포합물은정성진행연구.방법 응용U7(7~6)균균시험설계대영향포합적인소진행고찰,사선출최가포합공예;채용HPLC법,이β-세신미함량위지표연구포합전후석창포휘발유은정성.결과 석창포휘발유적최가포합공예위:β-CD:휘발유=3:1,β-CD:수=1:15,포합온도위30℃,교반시간위3 h;포합후,재고찰시간범위내석창포휘발유중β-세신미함량변화교소,RSD<5%.결론 사선출적포합공예은정가행,채용β-CD포합가유효제고석창포휘발유적은정성.
Objective To prepare the inclusion compound of volatile oil from Rhizoma Acori Tatarinowii and to study the stability of the compound . Methods U7 (7~6) uniform design was used for the optimization of conditions for the inclusion compound of Rhizoma Acori Tatarinowii . With β-asarone content as the evaluation index, the stability of inclusion compound was examined by HPLC. Results The optimal condition for the inclusion compound of Rhizoma Acori Tatarinowii was as follows: the ratio of β-CD and volatile oil being 3:1, β-CD : water being 1 : 15, inclusion temperature at 30 ℃, and stirring for 3 h. The stability of the inclusion compound wasis excellent and the RSD < 5 %. Conclusion The optimized process is stable and highly efficient. Inclusion with β-CD promotes the stability of volatile oil from Rhizoma Acori Tatarinowii.