中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2012年
16期
20-22
,共3页
心肌梗死%糖尿病%血糖
心肌梗死%糖尿病%血糖
심기경사%당뇨병%혈당
Myocardial infarction%Diabetes mellitus%Blood glucose
目的 探讨糖尿病(DM)心肌梗死(AMI)患者急性期血糖变化及对心功能的影响.方法 将73例AMI患者根据有无DM分为DM组(35例)和非DM组(38例),比较两组血糖变化特点及其与心功能的相关性.结果 DM组有33例(94.29％,33/35)空腹血糖升高,非DM组有14例(36.84％,14/38)应激性高血糖.DM组空腹血糖和糖化血红蛋白分别为(9.7±2.4) mmol/L、(10.13±1.95)％,均明显高于非DM组的(5.8±2.3) mmol/L、(7.22±1.87)％,差异有统计学意义(P＜0.05)；DM组肌酸激酶同工酶MB(CK-MB)和肌钙蛋白T(TnT)分别为(217±53) U/L、(6.2±3.7) mg/L,明显高于非DM组的(119±47) U/L、(3.4±2.9) mg/L,差异有统计学意义(P＜0.05).AMI后4周左心功能指标检测显示,DM组左室舒张末期容量(EDV)、左室收缩末期容量(ESV)分别为(81.7±10.8)、(47.6±10.7)ml,明显高于非DM组的(74.9±10.2)、(39.8±12.6) ml,而左室射血分数(LVEF)为(41.7±4.8)％,明显低于非DM组的(48.9±8.5)％,差异有统计学意义(P＜0.05).结论 AMI 合并DM患者急性期多伴有应激性血糖升高,心功能差,应积极进行干预.
目的 探討糖尿病(DM)心肌梗死(AMI)患者急性期血糖變化及對心功能的影響.方法 將73例AMI患者根據有無DM分為DM組(35例)和非DM組(38例),比較兩組血糖變化特點及其與心功能的相關性.結果 DM組有33例(94.29％,33/35)空腹血糖升高,非DM組有14例(36.84％,14/38)應激性高血糖.DM組空腹血糖和糖化血紅蛋白分彆為(9.7±2.4) mmol/L、(10.13±1.95)％,均明顯高于非DM組的(5.8±2.3) mmol/L、(7.22±1.87)％,差異有統計學意義(P＜0.05)；DM組肌痠激酶同工酶MB(CK-MB)和肌鈣蛋白T(TnT)分彆為(217±53) U/L、(6.2±3.7) mg/L,明顯高于非DM組的(119±47) U/L、(3.4±2.9) mg/L,差異有統計學意義(P＜0.05).AMI後4週左心功能指標檢測顯示,DM組左室舒張末期容量(EDV)、左室收縮末期容量(ESV)分彆為(81.7±10.8)、(47.6±10.7)ml,明顯高于非DM組的(74.9±10.2)、(39.8±12.6) ml,而左室射血分數(LVEF)為(41.7±4.8)％,明顯低于非DM組的(48.9±8.5)％,差異有統計學意義(P＜0.05).結論 AMI 閤併DM患者急性期多伴有應激性血糖升高,心功能差,應積極進行榦預.
목적 탐토당뇨병(DM)심기경사(AMI)환자급성기혈당변화급대심공능적영향.방법 장73례AMI환자근거유무DM분위DM조(35례)화비DM조(38례),비교량조혈당변화특점급기여심공능적상관성.결과 DM조유33례(94.29％,33/35)공복혈당승고,비DM조유14례(36.84％,14/38)응격성고혈당.DM조공복혈당화당화혈홍단백분별위(9.7±2.4) mmol/L、(10.13±1.95)％,균명현고우비DM조적(5.8±2.3) mmol/L、(7.22±1.87)％,차이유통계학의의(P＜0.05)；DM조기산격매동공매MB(CK-MB)화기개단백T(TnT)분별위(217±53) U/L、(6.2±3.7) mg/L,명현고우비DM조적(119±47) U/L、(3.4±2.9) mg/L,차이유통계학의의(P＜0.05).AMI후4주좌심공능지표검측현시,DM조좌실서장말기용량(EDV)、좌실수축말기용량(ESV)분별위(81.7±10.8)、(47.6±10.7)ml,명현고우비DM조적(74.9±10.2)、(39.8±12.6) ml,이좌실사혈분수(LVEF)위(41.7±4.8)％,명현저우비DM조적(48.9±8.5)％,차이유통계학의의(P＜0.05).결론 AMI 합병DM환자급성기다반유응격성혈당승고,심공능차,응적겁진행간예.
Objective To explore the blood glucose changes in diabetes mellitus (DM) patients with acute myocardial infarction(AMI) and its influence on heart function.Methods Seventy-three patients with AMI were divided into DM group (35 cases) with DM and non-DM group (38 cases) without DM.The blood glucose changes and the relationships with heart functon were observed in two groups.Results In DM group,33 cases (94.29％,33/35) had high fasting blood glucose,whereas in the non-DM group,14 cases (36.84％,14/38) had stress hyperglycemia.The levels of fasting blood glucose and glycosylated hemoglobin in the DM group were significantly higher than those in the non-DM group [(9.7 ± 2.4) mmol/L vs.(5.8 ± 2.3) mmol/L,(10.13 ±1.95 )％ vs.(7.22 ± 1.87)％,P ＜ 0.05 ].The levels of creatine kinase isozyme MB (CK-MB) and troponin T (TnT) in the DM group were significantly higher than those in the non-DM group [ ( 217 ± 53 ) U/L vs.( 119 ± 47 ) U/L,( 6.2 ± 3.7 ) mg/L vs.( 3.4 ± 2.9 ) mg/L,P ＜ 0.05 ].The detection of left ventricular function after 4 weeks of AMI showed that left ventricular end diastolic volume (EDV) and end systolic volume (ESV) of the DM group were significantly higher and LVEF was significantly lower than those of the non-DM group [ (81.7 ± 10.8 ) ml vs.(74.9 ± 10.2 ) ml,(47.6 ± 10.7 ) ml vs.(39.8 ±12.6) ml,(41.7 ± 4.8)％ vs.(48.9 ± 8.5)％,P＜ 0.05 ].Conclusions Patients with AMI and DM have high hyperglycemia and worse heart function.Therefore,intervention measures should be performed for these patients.
