CAJ | 학술논문

目的研究异丙酚联合芬太尼清醒镇静镇痛用于超导可视无痛人流术的有效性、安全性和可行性.方法选择ASA Ⅰ级拟行超导可视无痛人流术的患者60例,将其随机分为两组,清醒镇静镇痛组(A组)和对照组(B组),每组30例.A组:芬太尼1 μg/kg、异丙酚1.5 ～2.0mg/kg;B组:异丙酚2.0 ～ 3.0 mg/kg；A、B两组均视患者体动情况给予缓慢静脉注射异丙酚0.25 ～0.50 mg/kg观察记录两组患者术前和术中平均动脉压(MBP)、心率(HR)、呼吸频率(RR)、经皮脉搏血氧饱和度(SpO2),记录呼吸抑制、心动过缓及警觉/镇静评分.结果两组患者在给药结束时的MBP、HR、Sp02均较基础值有显著降低(P＜0.05).手术开始后略有回升,但两组间的变化幅度比较差异无统计学意义(P＞0.05),A组发生重度呼吸抑制的比率明显少于B组(P＜0.05),A组患者术毕神志恢复较B组迅速,差异有统计学意义(P＜0.05) 结论异丙酚联合芬太尼清醒镇静镇痛用于超导可视无痛人流术能达到满意的麻醉效果,是一种安全、有效、可行的麻醉方法.
목적 연구이병분연합분태니청성진정진통용우초도가시무통인류술적유효성、안전성화가행성.방법 선택ASA Ⅰ급의행초도가시무통인류술적환자60례,장기수궤분위량조,청성진정진통조(A조)화대조조(B조),매조30례.A조:분태니1 μg/kg、이병분1.5 ～2.0mg/kg;B조:이병분2.0 ～ 3.0 mg/kg；A、B량조균시환자체동정황급여완만정맥주사이병분0.25 ～0.50 mg/kg관찰기록량조환자술전화술중평균동맥압(MBP)、심솔(HR)、호흡빈솔(RR)、경피맥박혈양포화도(SpO2),기록호흡억제、심동과완급경각/진정평분.결과 량조환자재급약결속시적MBP、HR、Sp02균교기출치유현저강저(P＜0.05).수술개시후략유회승,단량조간적변화폭도비교차이무통계학의의(P＞0.05),A조발생중도호흡억제적비솔명현소우B조(P＜0.05),A조환자술필신지회복교B조신속,차이유통계학의의(P＜0.05) 결론 이병분연합분태니청성진정진통용우초도가시무통인류술능체도만의적마취효과,시일충안전、유효、가행적마취방법.
Objective To study the validity,safety and feasibility of conscious sedation analgesia with propofol and fentanyl infusion for superconducting visual painless abortion.Methods Sixty ASA (American society of anesthesiologist) Ⅰ patients undergoing superconducting visual painless abortion were randomly divided into two groups:conscious sedation analgesia group with propofol and fentanyl,control group with propofol only.The levels of MAP,HR,SpO2 and recovery time and OAA/S scoles were evaluated,analyzed and compared during operation.Results The changes of MBP,HR,SpO2 in control group in operation were obvious compared with baseline before operation,and which of conscious sedation analgesia group were relatively stable.Lower respiratory supression and more rapidly recover consciousness was observed among conscious sedation analgesia group.Conclusions Conscious sedation analgesia with propofol and fentanyl infusion is feasible for superconducting visual painless abortion,which has advantages of saving drug,safety and good effect.