CAJ | 학술논문

半乳糖凝集素能识别和特异性结合β-半乳糖苷,调控肿瘤细胞转化、生存、促进肿瘤细胞迁移和转移等,与肿瘤的诊断、进展和预后相关,还能作为免疫调节分子调节免疫细胞生存、活化、增殖、分化,是肿瘤免疫微环境的组成成分之一.
반유당응집소능식별화특이성결합β-반유당감,조공종류세포전화、생존、촉진종류세포천이화전이등,여종류적진단、진전화예후상관,환능작위면역조절분자조절면역세포생존、활화、증식、분화,시종류면역미배경적조성성분지일.
Galectins can recognize and specifically bind to β-galactosidase,and regulate the transformation and survival of tumor cells,and promote the migration and metastasis of tumor cells,etc.Galectins correlate with tumor diagnosis,progression and prognosis.Galectias also can serve as immunoregulatory molecules to regulate the survival,activation,proliferation and differentiation of immune cells,and are components of tumor immune microenvironment.