中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2010年
8期
810-812
,共3页
梁延东%朱月香%余春晓%黄徵
樑延東%硃月香%餘春曉%黃徵
량연동%주월향%여춘효%황징
煤工尘肺%睡眠呼吸暂停综合征%多器官功能障碍
煤工塵肺%睡眠呼吸暫停綜閤徵%多器官功能障礙
매공진폐%수면호흡잠정종합정%다기관공능장애
Coal worker's pneumoconiosis%Sleep apnea syndrome%Multiple-organ dysfunction
目的 综合分析煤工尘肺合并睡眠呼吸暂停的临床特征并评价其意义.方法 对2006年2月至2009年12月我院40例住院煤工尘肺合并睡眠呼吸暂停患者进行多导睡眠监测,并对血常规、尿常规、血压、生化指标等进行检测.结果 煤工尘肺合并睡眠呼吸暂停主要表现为重叠低氧血症以及多器官功能损害,如高血压和心、肺、肾功能损害,红细胞增多,血糖、血脂、血尿酸升高等,并形成恶性循环加重上述损害.结论 煤工尘肺合并睡眠呼吸暂停可引起严重的低氧血症及高碳酸血症,并造成多器官系统损害,临床应充分认识,早期、合理和有效的治疗可逆转或延迟多器官功能的进一步损害,明显改善预后.
目的 綜閤分析煤工塵肺閤併睡眠呼吸暫停的臨床特徵併評價其意義.方法 對2006年2月至2009年12月我院40例住院煤工塵肺閤併睡眠呼吸暫停患者進行多導睡眠鑑測,併對血常規、尿常規、血壓、生化指標等進行檢測.結果 煤工塵肺閤併睡眠呼吸暫停主要錶現為重疊低氧血癥以及多器官功能損害,如高血壓和心、肺、腎功能損害,紅細胞增多,血糖、血脂、血尿痠升高等,併形成噁性循環加重上述損害.結論 煤工塵肺閤併睡眠呼吸暫停可引起嚴重的低氧血癥及高碳痠血癥,併造成多器官繫統損害,臨床應充分認識,早期、閤理和有效的治療可逆轉或延遲多器官功能的進一步損害,明顯改善預後.
목적 종합분석매공진폐합병수면호흡잠정적림상특정병평개기의의.방법 대2006년2월지2009년12월아원40례주원매공진폐합병수면호흡잠정환자진행다도수면감측,병대혈상규、뇨상규、혈압、생화지표등진행검측.결과 매공진폐합병수면호흡잠정주요표현위중첩저양혈증이급다기관공능손해,여고혈압화심、폐、신공능손해,홍세포증다,혈당、혈지、혈뇨산승고등,병형성악성순배가중상술손해.결론 매공진폐합병수면호흡잠정가인기엄중적저양혈증급고탄산혈증,병조성다기관계통손해,림상응충분인식,조기、합리화유효적치료가역전혹연지다기관공능적진일보손해,명현개선예후.
Objective We studied the clinical features and its significance of coal worker's pneumoconiosis combined with sleep apnea Methods In 40 patients with coal worker's pneumoconiosis combined with sleep apnea hospitalized from February 2006 to December 2009, polysomnography ( PSG) , blood routine, urine routine, blood pressure and biochemical indicators were measured and analyzed. Results Patients with coal worker' s pneumoconiosis combined with sleep apnea manifested mainly as duplicate hypoxemia and multi-organ dysfunction: high blood pressure, dysfunction of heart, lung and kidney, increase of serum glucose, blood lipids, blood uric acid and finally led a vicious cycle to aggravate the above mentioned damage. Conclusions In clinical, multiple-organ dysfunction resulted from severe hypoxemia and hypercapnia caused by coal worker's pneumoconiosis combined with sleep apnea, should be fully aware and give ational and effective treatment early to reverse or delay the further function damages of multiple organs, and therefore significantly improve the prognosis.