CAJ | 학술논문

目的探讨奥曲肽治疗早期术后粘连性肠梗阻的疗效.方法 38例早期术后粘连性肠梗阻患者分为治疗组(20例)和对照组(18例),两组间年龄、性别及肠梗阻的病因比较差异无统计学意义(P＞0.05).治疗组20例给予奥曲肽0.1 mg,每6小时1次或每8小时1次,连用4～14 d.同时按常规治疗禁食,补液及纠正水、电解质失衡;18例对照组按常规治疗禁食,补液及纠正水、电解质失衡.结果治疗组的治愈率为75%,对照组的治愈率为56%.两组比较差异无统计学意义(P＞0.05).但治疗组的症状缓解时间短,平均肛门排气时间为(3.5±1.6)d,平均住院时间(8.6 ±4.2)d:对照组症状缓解时间长,平均肛门排气时间为(6.7±2.5)d,平均住院时间(11.2±2.2)d.两组比较差异有统计学意义(P＜0.05).结论奥曲肽在治疗早期术后粘连性肠梗阻上是一种新的、安全、有效的药物.
목적 탐토오곡태치료조기술후점련성장경조적료효.방법 38례조기술후점련성장경조환자분위치료조(20례)화대조조(18례),량조간년령、성별급장경조적병인비교차이무통계학의의(P＞0.05).치료조20례급여오곡태0.1 mg,매6소시1차혹매8소시1차,련용4～14 d.동시안상규치료금식,보액급규정수、전해질실형;18례대조조안상규치료금식,보액급규정수、전해질실형.결과 치료조적치유솔위75%,대조조적치유솔위56%.량조비교차이무통계학의의(P＞0.05).단치료조적증상완해시간단,평균항문배기시간위(3.5±1.6)d,평균주원시간(8.6 ±4.2)d:대조조증상완해시간장,평균항문배기시간위(6.7±2.5)d,평균주원시간(11.2±2.2)d.량조비교차이유통계학의의(P＜0.05).결론 오곡태재치료조기술후점련성장경조상시일충신적、안전、유효적약물.
Objective To investigate the effect of octreotide in early postoperative inflammatory bowel ob-struction. Methods Thirty - eight cases of early postoperative inflammatory bowel obstruction were divided into two groups:healing group (20 cases) and control group (18 cases). There was no significant difference be-tween the two groups on age, gender or cause for disease ( P ＞ 0.05 ). Twenty patients of healing group were treated with octreotide 0.1 mg, q6h or q8h, fasting, gastrointestinal decompression,fluid and electrolyte sup-plement for 4 - 14 days. The patients of control group were treated for 4 - 14 days without octreotide. Results After treatment,the cure rates in the healing group and the control were 75% and 56% ,respectively ( P ＞0. 05). In healing group, remission time of symptoms was short, the average anal exhaust time was ( 3.5 ±1.6) days, the average hospitalization time was (8.6 ± 4.2 ) days. While those in the control were long,(6.7 ± 2.5 ) days and ( 11.2 ± 2.2 ) days, respectively ( P ＜ 0.05 ). Conclusion Octreotide is a new safe and effect drug in the treatment of early postoperative inflammatory bowel obstruction.