CAJ | 학술논문

目的:研究本体感觉训练对中重型儿童血友病患者下肢靶关节出血频率的影响.方法:本研究为前瞻性随机对照临床研究,将40例中重型血友病患儿随机分成2组,分别为单纯预防性低剂量凝血因子替代组和预防性低剂量凝血因子替代+本体感觉训练组,每组疗程8周.观察比较治疗期间、治疗结束1个月、3个月时两组出血频率.并对随访3个月时两组出血频率分别与治疗前进行比较.结果:治疗期间和治疗后1个月本体感觉训练组出血频率较对照组显著减少,随访3个月时与对照组比较差异无显著性,但分别与治疗前相比,差异均有显著性.结论:本体感觉训练在预防血友病儿童再次出血和减少出血次数方面具有重要作用,但是,治疗停止后随着时间的推移差异逐渐减弱消失.因此,儿童血友病患者应该坚持进行长期的、规律性的治疗性训练,从而保持本体感觉功能,预防和减少下肢靶关节的出血.
목적:연구본체감각훈련대중중형인동혈우병환자하지파관절출혈빈솔적영향.방법:본연구위전첨성수궤대조림상연구,장40례중중형혈우병환인수궤분성2조,분별위단순예방성저제량응혈인자체대조화예방성저제량응혈인자체대+본체감각훈련조,매조료정8주.관찰비교치료기간、치료결속1개월、3개월시량조출혈빈솔.병대수방3개월시량조출혈빈솔분별여치료전진행비교.결과:치료기간화치료후1개월본체감각훈련조출혈빈솔교대조조현저감소,수방3개월시여대조조비교차이무현저성,단분별여치료전상비,차이균유현저성.결론:본체감각훈련재예방혈우병인동재차출혈화감소출혈차수방면구유중요작용,단시,치료정지후수착시간적추이차이축점감약소실.인차,인동혈우병환자응해견지진행장기적、규률성적치료성훈련,종이보지본체감각공능,예방화감소하지파관절적출혈.
Objective:To study if proprioception training will reduce bleeding episodes in target joints of low extremities in children with moderate-severe hemophilia. Method:Forty moderate-severe hemophilia children were enrolled in this prospective randomized clinical trial and divided into group A and B.Children in group A and B were prescribed secondary prophylaxis with low dose factor concentrate replacement for 8 weeks,and group B received proprioception training for 8 weeks additionally. Bleeding episodes in target joints of low extremities were observed during treatment,1 month and 3 months after treatment,respectively. Result:Dunng treatment and follow up 1 month,bleeding episodes in target joints of low extremities in group B were less than group A statistically,while in follow up 3 months,there was no difference between two groups statistically. Conclusion:Proprioception training will prevent and reduce target joints bleeding episodes,but this effect will recede gradually after training stopped.So in hemophilia patients especially children,individualized,long-term and regular therapeutic exercises should have to keep to improve proprioception function in order to prevent and reduce bleeding episodes in target joints.