CAJ | 학술논문

自1997年中国香港特别行政区报道首例人感染H5N1禽流感病毒以来,截至2008年9月10日,这场在禽类中史无前例地持续流行、造成了人类感染并具有高病死率的疫情已经波及到15个国家和地区,总发病387例,死亡245例,其中我国疫情30例,病死率超过60%,防控形势十分严峻.本文旨在整理分析2005年以来世界卫生组织和全球对禽流感病毒临床防治研究成果及人感染H5N1禽流感病例报道的最新信息,力求提供一个防治人禽流感方面的较为全面而清晰的介绍.
자1997년중국향항특별행정구보도수례인감염H5N1금류감병독이래,절지2008년9월10일,저장재금류중사무전례지지속류행、조성료인류감염병구유고병사솔적역정이경파급도15개국가화지구,총발병387례,사망245례,기중아국역정30례,병사솔초과60%,방공형세십분엄준.본문지재정리분석2005년이래세계위생조직화전구대금류감병독림상방치연구성과급인감염H5N1금류감병례보도적최신신식,력구제공일개방치인금류감방면적교위전면이청석적개소.
Highly pathogenic H5N1 avian influenza virus(AIV) has spread unprecedentedly across the world since the first outbreak of human cases was reported in 1997 in Hong Kong, China. Until June 19th,2008,H5N1 virus resulted in sporadic but severe even fatal human cases in 15 countries,243 died in 385 reported human H5N1 infections,including 20 in China,and the overall mortality was more than 60%. These new appeared viruses and their capacity of transmission from birds to humans have raised a great deal of concern for a potential pandemic,and world health organization has promulgated a few recommendations or guidelines. This review provides an up-to-date information of research in H5N1 virus infection since 2005, and summarizes the epidemiology, clinical features, pathology, diagnosis, current therapeutic options and prevention strategies of H5N1 infection in humans.