CAJ | 학술논문

目的探讨单侧海马结构损伤患者在工作记忆时分别记忆颜色、空间及颜色-空间整合时的认知行为特点.方法 13例单侧海马结构损伤患者和13名年龄、性别及文化程度相匹配的健康对照者分别从事颜色、位置和颜色-位置整合三种工作记忆延迟匹配样本任务,计算机记录其行为反应时间和正确率,并统计学分析.结果海马结构损伤组在颜色记忆或空间记忆任务时的行为反应时间[(1167.46±99.52)ms;(915.85±46.19)ms]和正确率[(79.23±2.42)%;(81.77±2.55)%]较对照组[(1132.61±97.90)ms,(80.69±1.55)%;(888.77±65.94)ms,(83.69±-2.63)%]差异均无统计学意义(P>0.05);颜色-空间整合记忆时其反应时间[(1146.69±51.93)ms]长于健康对照组[(1073.08±51.42)ms],而反应正确率[(73.92±2.87)%]却较对照组[(83.92±2.72)%]明显下降,且差异均有统计学意义(P<0.05).结论海马结构在视觉-空间整合的工作记忆中起重要作用.
목적 탐토단측해마결구손상환자재공작기억시분별기억안색、공간급안색-공간정합시적인지행위특점.방법 13례단측해마결구손상환자화13명년령、성별급문화정도상필배적건강대조자분별종사안색、위치화안색-위치정합삼충공작기억연지필배양본임무,계산궤기록기행위반응시간화정학솔,병통계학분석.결과 해마결구손상조재안색기억혹공간기억임무시적행위반응시간[(1167.46±99.52)ms;(915.85±46.19)ms]화정학솔[(79.23±2.42)%;(81.77±2.55)%]교대조조[(1132.61±97.90)ms,(80.69±1.55)%;(888.77±65.94)ms,(83.69±-2.63)%]차이균무통계학의의(P>0.05);안색-공간정합기억시기반응시간[(1146.69±51.93)ms]장우건강대조조[(1073.08±51.42)ms],이반응정학솔[(73.92±2.87)%]각교대조조[(83.92±2.72)%]명현하강,차차이균유통계학의의(P<0.05).결론 해마결구재시각-공간정합적공작기억중기중요작용.
Objective To investigate the behavioral characteristic of the human with half hippocampal formation lesion engaged in color task, location task and color-location associated task of working memory. Meth-ods The behavioral performances were recorded from 13 patients of half hippocampal formation lesion and 13 healthy subjects while performing three binding tasks. At-test was adopted. Results In color task or location task, behavioral performances of reaction time [(1167.46±99.52) ms;(915.85±46.19) ms] and accuracy [(79.23±2.42) % ;(81.77±2.55) % ] of patients had no statistical significance of the healthy subjects [(1132.61±97.90) ms, (80.69±1.55) % ;(888.77±65.94) ms, (83.69±2.63) %]. But that in associated task of patients were statistical significant worse. In color-location task, the reaction time[(1146.69±51.93)ms] of patients is longer than that of the healthy subjects [(1073.08±51.42)ms], and the reaction accuracy [(73.92 ±2.87)%] of patients was worse than that of healthy subjects [(83.92±2.72)%]. Conclusion The hipp-ocampal formation plays a significant role for working memory of simple visuo-spatial associations.