中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
15期
41-42
,共2页
CD10%CD13%甲状腺转录因子-1%肺癌%免疫组织化学
CD10%CD13%甲狀腺轉錄因子-1%肺癌%免疫組織化學
CD10%CD13%갑상선전록인자-1%폐암%면역조직화학
CD10%CD13%TTF-1%Lung cancer%Immunohistochemistry
目的 评价共同急性淋巴母细胞性白血病抗原(CD10、CD13)及甲状腺转录因子-1(TTF-1)在原发性肺癌表达的特异性及敏感性,探讨以上标记物在原发性肺癌的诊断及鉴别诊断中的意义.方法 收集原发性肺癌97例,其中腺癌43例,鳞癌49例,小细胞癌4例,细支气管肺泡癌1例,采用SP法进行CD10、CD13及TTF-1检测.结果 在肺腺癌、鳞癌、小细胞癌及支气管肺泡癌中的阳性表达率,CD10分别为53.5%、20.4%、25.0%、0;CD13分别为69.7%、30.6%、25.0%、0;TTF-1分别为83.7%、6.1%、75.0%、0.结论 CD10、CD13和TTF-1在原发性肺癌的诊断与鉴别诊断中有一定意义.
目的 評價共同急性淋巴母細胞性白血病抗原(CD10、CD13)及甲狀腺轉錄因子-1(TTF-1)在原髮性肺癌錶達的特異性及敏感性,探討以上標記物在原髮性肺癌的診斷及鑒彆診斷中的意義.方法 收集原髮性肺癌97例,其中腺癌43例,鱗癌49例,小細胞癌4例,細支氣管肺泡癌1例,採用SP法進行CD10、CD13及TTF-1檢測.結果 在肺腺癌、鱗癌、小細胞癌及支氣管肺泡癌中的暘性錶達率,CD10分彆為53.5%、20.4%、25.0%、0;CD13分彆為69.7%、30.6%、25.0%、0;TTF-1分彆為83.7%、6.1%、75.0%、0.結論 CD10、CD13和TTF-1在原髮性肺癌的診斷與鑒彆診斷中有一定意義.
목적 평개공동급성림파모세포성백혈병항원(CD10、CD13)급갑상선전록인자-1(TTF-1)재원발성폐암표체적특이성급민감성,탐토이상표기물재원발성폐암적진단급감별진단중적의의.방법 수집원발성폐암97례,기중선암43례,린암49례,소세포암4례,세지기관폐포암1례,채용SP법진행CD10、CD13급TTF-1검측.결과 재폐선암、린암、소세포암급지기관폐포암중적양성표체솔,CD10분별위53.5%、20.4%、25.0%、0;CD13분별위69.7%、30.6%、25.0%、0;TTF-1분별위83.7%、6.1%、75.0%、0.결론 CD10、CD13화TTF-1재원발성폐암적진단여감별진단중유일정의의.
Objective To evaluate the specificity and sensitivity of CD10, CD13 and TTF-1 in primary lung carcinomas and to investigate its significance in diagnosis and differential diagnosis of pulmonary carcinomas. Methods Collected 97 cases including 43 cases of primary pulmonary adenocarcinomas,49 cases of primary pulmonary squamous cell carcinomas, 4 cases of pulmonary small cell carcinomas and 1 case of primary bronchioloalveolar carcinoma, the expressions of CD10, CD13 and TTF-1 were detected using SP immunohistochemistry. Results Positive expression in primary pulmonary adenocarcinomas and primary pulmonary squamous cell carcinomas and pulmonary small cell carcinomas and primary bronchioloalveolar carcinoma,CD10 were 53.%, 20.4%,25.0%,0;CD13 were 69.7%, 30.6%,25.0%,0;TTF-1 were 83.7%,6.1%,75.0%,0;respectively.Conclusions CD10, CD13 and TTF-1 have certain significances in primary lung cancer diagnosis and differential diagnosis.
