医学信息（内·外科版）
醫學信息（內·外科版）
의학신식（내·외과판）
MEDICAL INFORMATION SECTION OF OPERATIVE SURGERY
2009年
6期
522-524
,共3页
胸腺肽%抗痨%浸润型肺结核%内皮素
胸腺肽%抗癆%浸潤型肺結覈%內皮素
흉선태%항로%침윤형폐결핵%내피소
thymosin%anti-tuberculosis%infiltrative pulmonary tuberculosis%endothelin
目的 观察胸腺肽辅助治疗对浸润型肺结核血浆内皮素(endotbelin,ET)变化的影响及其临床疗效.方法 将128例浸润型肺结核患者随机分为治疗组68例和对照组60例,观察两组患者治疗前后血浆内皮素变化、肺部病灶改变及痰菌阴转情况.结果 治疗前两组患者血浆内皮素均明显增高P>0.05,两组治疗后自身比较血浆内皮素均有明显降低,治疗组优于对照组,有显著性差异P<0.01.治疗2个月后痰菌阴转结果 ,治疗组为94%,对照组为73.3%,治疗组明显高于对照组,具有显著性差异P<0.01.病灶吸收率,治疗组为97%、对照组为76.6%,治疗组优与对照组,差异显著P<0.01.结论 胸腺肽辅助治疗肺结核,可降低血浆内皮素,缩短痰菌转阴时间,加快肺部病灶吸收.
目的 觀察胸腺肽輔助治療對浸潤型肺結覈血漿內皮素(endotbelin,ET)變化的影響及其臨床療效.方法 將128例浸潤型肺結覈患者隨機分為治療組68例和對照組60例,觀察兩組患者治療前後血漿內皮素變化、肺部病竈改變及痰菌陰轉情況.結果 治療前兩組患者血漿內皮素均明顯增高P>0.05,兩組治療後自身比較血漿內皮素均有明顯降低,治療組優于對照組,有顯著性差異P<0.01.治療2箇月後痰菌陰轉結果 ,治療組為94%,對照組為73.3%,治療組明顯高于對照組,具有顯著性差異P<0.01.病竈吸收率,治療組為97%、對照組為76.6%,治療組優與對照組,差異顯著P<0.01.結論 胸腺肽輔助治療肺結覈,可降低血漿內皮素,縮短痰菌轉陰時間,加快肺部病竈吸收.
목적 관찰흉선태보조치료대침윤형폐결핵혈장내피소(endotbelin,ET)변화적영향급기림상료효.방법 장128례침윤형폐결핵환자수궤분위치료조68례화대조조60례,관찰량조환자치료전후혈장내피소변화、폐부병조개변급담균음전정황.결과 치료전량조환자혈장내피소균명현증고P>0.05,량조치료후자신비교혈장내피소균유명현강저,치료조우우대조조,유현저성차이P<0.01.치료2개월후담균음전결과 ,치료조위94%,대조조위73.3%,치료조명현고우대조조,구유현저성차이P<0.01.병조흡수솔,치료조위97%、대조조위76.6%,치료조우여대조조,차이현저P<0.01.결론 흉선태보조치료폐결핵,가강저혈장내피소,축단담균전음시간,가쾌폐부병조흡수.
Objective To observe the clinical effect of thymosin adjuvant therapy, and serum endothelin changes of infiltrative pulmonary tuberculosis. Methods One hundred and twenty-eight patients with infiltrative pulmonary tuberculosis were randomly divided into therapy group (68 cases) and control group (60 cases). Changes of plasma en-dotbelin, pulmonary lesions and sputum negative conversion were observed. Results Plasma endothelin of both groups increased (P > 0. 05) before the treatment, while plasma endothelin of both groups decreased significantly after the treatment. Rate of sputum negative conversion after 2 months' treatment were 94.0% and 73.3% respectively,and therapy group was higher than control group(P <0.01). Conclusions Thymosin adjuvant therapy can improve endo-thelial function, decrease plasma endothelin concentration, shorten sputum negative conversion time, and speed up ab-sorption of pulmonary lesions.
