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化学研究与应用 화학연구여응용
CHEMICAL RESEARCH AND APPLICATION
2010年 3期 370-373 ,共4页

郑园%田军%吴立霞%谭美珊%刘小平%杨乐敏%倪春林

정완%전군%오립하%담미산%류소평%양악민%예춘림

苄基取代吡啶类季铵盐%合成%杀菌活性芐基取代吡啶類季銨鹽%閤成%殺菌活性
변기취대필정류계안염%합성%살균활성
benzyl substituted pyridine quaternary ammonium salts%synthesis%antibacterial properties

Four benzyl substituted pyridine bromide quaternary ammonium salts, 1-benzyl-2'-methylpyridinium bromide ([Bz-2-CH_3Py] Br), 1-benzyl-4'-methylpyridinium bromide ([Bz-4-CH_3Py] Br), 1-benzyl-4'-aminopyridinium bromide ([Bz-4-NH_2Py] Br) and 1-benzyl-4'-dimethylaminopyridinium bromide ([BzDMAP] Br), were synthesized by the reaction of benzyl bromide and 2-methylpyridine,4-methylpyridine,4-aminopyridine or 4-dimethylaminopyridine. Their components and structures were characterized by elemental analyses, infrared spectra, electronic spray mass spectra and conductivity. The experimental results of antibacterial activities indicated that the four salts exhibited good antibacterial properties for colibacillus, bacillus subtilus, aurococcus and bacillus thuringiensis.