CAJ | 학술논문

目的探讨儿童血管畸形经股动脉介入治疗的方法、疗效及并发症.方法收集2009年1月至2011年6月经介入治疗高流量血管畸形20例,男8例,女12例,年龄4个月14d至14岁7个月,中位年龄4岁5个月,发生于四肢血管畸形最为常见有8例(40％),颈部1例,腋下1例,肩背部3例,腰臀部1例,臀部1例,下肢及会阴1例,肝脏1例,脾脏1例,肾脏2例.治疗方法分别为:①外周血管畸形进行经导管局部灌注硬化剂治疗;②内脏血管畸形进行经导管栓塞术或经导管栓塞加局部灌注硬化剂治疗.结果 20例血管畸形患儿介入术后临床症状、体征明显改善,术后2个月至2.5年随访,16例外周血管畸形患儿中8例、5例、3例分别经1、2、3个疗程治疗,显效14例(14/16,8 7.5％),有效2例(2/16,12.5％),无效0例(0％)；4例内脏血管畸形患儿一个疗程治愈,治愈率100％(4/4).并发症:16例外周血管畸形患儿介入术后,出现病变部位轻度肿胀不适15例,中度肿胀不适1例,疼痛加剧1例,局部皮温改变1例,病变部位远期感染1例,低热1例；4例内脏血管畸形患儿介入术后,出现一过性轻度肝功能损害和低热1例,短暂性腹痛1例.结论采用经股动脉血管内介入治疗血管畸形是一种微创安全、疗效显著的方法.
목적 탐토인동혈관기형경고동맥개입치료적방법、료효급병발증.방법 수집2009년1월지2011년6월경개입치료고류량혈관기형20례,남8례,녀12례,년령4개월14d지14세7개월,중위년령4세5개월,발생우사지혈관기형최위상견유8례(40％),경부1례,액하1례,견배부3례,요둔부1례,둔부1례,하지급회음1례,간장1례,비장1례,신장2례.치료방법분별위:①외주혈관기형진행경도관국부관주경화제치료;②내장혈관기형진행경도관전새술혹경도관전새가국부관주경화제치료.결과 20례혈관기형환인개입술후림상증상、체정명현개선,술후2개월지2.5년수방,16예외주혈관기형환인중8례、5례、3례분별경1、2、3개료정치료,현효14례(14/16,8 7.5％),유효2례(2/16,12.5％),무효0례(0％)；4례내장혈관기형환인일개료정치유,치유솔100％(4/4).병발증:16예외주혈관기형환인개입술후,출현병변부위경도종창불괄15례,중도종창불괄1례,동통가극1례,국부피온개변1례,병변부위원기감염1례,저열1례；4례내장혈관기형환인개입술후,출현일과성경도간공능손해화저열1례,단잠성복통1례.결론 채용경고동맥혈관내개입치료혈관기형시일충미창안전、료효현저적방법.
Objective To review the efficacy and complications of interventional treatment for vascular malformation in children.Methods Twenty children with vascular malformation (8 males:12females,age ranged from 0.38 years to 14.58 years,the median age 4.42 years) were accepted in this study.Treatment methods contained transcatheter local sclerotherapy,transcatheter cmbolization and transcatheter embolization combined with local sclerosing agents.Results The extremities were the most commonly affected site (8/20,40％).Other locations were cervical region,armpit,shoulder and back,lumbar,gluteal region,perineum,liver,spleen and kidney.Symptom and physical sign improved greatly after interventional treatment.from observations done during a follow-up period between 2 months to 2.5 years.In 16 children with peripheral vascular malformation,8 cases received 1course of treatment,only 2 courses were given in 5 patients,and 3 courses given in 3 cases.Results were excellent in 14 cases (14/16,87.5％),moderately effective in 2 cases (2/16,12.5％).In 4 cases with visceral vascular malformation,one course of treatment was enough to cure all (4/4,100％).Treatment-related complications such as local soft tissue edema and discomfort aggravating pain of the treated area,fever,and short-term liver damage were reported.Conclusions Interventional treatment for vascular malformation in children is mnimally invasive,safe and effective.