CAJ | 학술논문

背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低.目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系.方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表(Personal and Social Performance Scale,PSP)中文版、临床疗效总评量表-病情严重程度量表(Clinical GlobalImpression-Severity,CGI-S)、阳性和阴性症状量表(Positive and Negative Symptom Scale,PANSS)、字母-数字排序以及香港文字记忆学习测试等项目的评定.结果患者PANSS量表的3个临床分量表的分值和社会功能总体评估(PSP总分和CGI-S分值)之间存在明显负相关.患者的神经认知测定结果与症状或社会功能状况均无关.结论对于急性期住院精神分裂症患者而言,临床症状的严重度-而非神经认知缺损程度,与其社会功能水平密切相关.
배경이왕연구표명정신분렬증환자적신경인지결손화정신병성증상회도치기직업화사회공능강저.목적평고중국정신분렬증남성주원환자적신경인지화정신병성증상여사회심리공능지간적관계.방법선취상해시정신위생중심적51례주원남성정신분렬증환자,기중40례환자최종완성료개체화사회공능량표(Personal and Social Performance Scale,PSP)중문판、림상료효총평량표-병정엄중정도량표(Clinical GlobalImpression-Severity,CGI-S)、양성화음성증상량표(Positive and Negative Symptom Scale,PANSS)、자모-수자배서이급향항문자기억학습측시등항목적평정.결과환자PANSS량표적3개림상분량표적분치화사회공능총체평고(PSP총분화CGI-S분치)지간존재명현부상관.환자적신경인지측정결과여증상혹사회공능상황균무관.결론대우급성기주원정신분렬증환자이언,림상증상적엄중도-이비신경인지결손정도,여기사회공능수평밀절상관.
Background: Prior research has determined that impairment in neurocognition and psychiatric symptoms contribute to reduced occupational and social functioning in schizophrenia.Objective: Evaluate the relationships of neurocognition, psychiatric symptoms, and psychosocial functioning in male inpatients with schizophrenia in China.Methods: Fifty-one male patients currently hospitalised at the Shanghai Mental Health Center with a diagnosis of schizophrenia were recruited and 40 of them were included in the final analysis. Participants were assessed with Chinese versions of the Personal and Social Performance Scale (PSP), Clinical Global Impression-Severity (CGI-S) scale, Positive and Negative Symptom Scale (PANSS), Letter-Number Sequencing Task, and Hong Kong List Learning Test.Results: Robust negative correlations were found between three clinical subscale scores derived from the PANSS and the global measures of social function (the total PSP score and the CGI-S score). Performance on the neurocognitive tasks was not associated with either symptoms or social functioning status.Conclusions: Among inpatients in the acute phase of schizophrenia, the severity of the clinical symptoms-not the degree of the neurocognitive impairment-is closely associated with the level of social functioning.