CAJ | 학술논문

[目的]测定生物和环境样品中的重金属及其化学形态,从而更准确地评价其对人体健康的潜在危害,并且监测重金属从环境基质到人体的迁移途径.[方法]利用微波辅助萃取进行样品预处理,离子色谱分离重金属不同化学形态,电感耦合等离子体质谱进行检测.[结果]微波辅助萃取能够将重金属的不同无机和有机形态从样品基质中有效分离,分离过程中金属形态不发生变化.将离子色谱和电感耦合等离子体质谱在线联用,辅以稳定性同位素标记,可以准确测定生物和环境样品中的金属(铅、铬和汞)形态.[结论]提高生物和环境样品中重金属检测的灵敏度,并且测定金属的化学形态,可以对评价重金属对人体健康的潜在危害提供重要信息.
[목적]측정생물화배경양품중적중금속급기화학형태,종이경준학지평개기대인체건강적잠재위해,병차감측중금속종배경기질도인체적천이도경.[방법]이용미파보조췌취진행양품예처리,리자색보분리중금속불동화학형태,전감우합등리자체질보진행검측.[결과]미파보조췌취능구장중금속적불동무궤화유궤형태종양품기질중유효분리,분리과정중금속형태불발생변화.장리자색보화전감우합등리자체질보재선련용,보이은정성동위소표기,가이준학측정생물화배경양품중적금속(연、락화홍)형태.[결론]제고생물화배경양품중중금속검측적령민도,병차측정금속적화학형태,가이대평개중금속대인체건강적잠재위해제공중요신식.
[Objective]To measure metals in both environmental and biological matrices which allows for more accurate assessment of risk to human health as well as monitoring of the pathway from matrix to human incorporation. [ Methods] Microwave assisted extraction for sample preparation, ion chromatography for analyte separation, and inductively coupled plasma/mass spectrometry (ICP/MS) for detection.[ Results ] The microwave assisted extraction demonstrated its utility in removing both inorganic and organic metal species from their matrix without species interconversion. The on - line coupling of IC and ICP/ MS,in conjunction with stable isotope labels, was successfully applied to the determination of metal species (specifically lead, chromium and mercury)in various environmental and biological samples. [Conclusion]The development of methods for more sensitive measurement as well as the determination of the chemical species of the metal analyte can provide critical information in assessing its potential risk to human health.