中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2008年
31期
22-24
,共3页
高血压%颈动脉疾病%颈动脉狭窄%清晨血压高峰
高血壓%頸動脈疾病%頸動脈狹窄%清晨血壓高峰
고혈압%경동맥질병%경동맥협착%청신혈압고봉
Hypertension%Carotid artery disease%Carotid stenosis%Peak morning blood pressure
目的 探讨清晨血压高峰与颈动脉粥样硬化的关系.方法 97例轻、中度原发性高血压患者行24h动态血压监测,并根据监测结果将之分为存在清晨血压高峰组(MP+组,31例)和无清晨血压高峰组(MP-组,66例).所有患者经彩色多普勒超声检测颈动脉内膜-中层厚度(IMT)和粥样硬化斑块的发生情况,观察清晨血压高峰与颈动脉IMT和动脉粥样硬化斑块发生率的相关性.结果 MP+组患者颈总动脉(CCA)、颈总动脉分叉处(CAB)和颈内动脉(ICA)的IMT均高于MP-组[(1.02±0.36)ram比(0.86±0.22)mm、(1.14±0.39)mm比(0.96±0.26)mm和(0.94±0.30)mm比(0.82±0.18)mln,P<0.05].MP+组颈动脉粥样硬化斑块的发生率为64.5%(20/31),MP-组为42.4%(28/66),两组比较差异有统计学意义(P<0.05).结论 清晨血压高峰与颈动脉粥样硬化相关,清晨血压高峰可加速动脉粥样硬化的形成和发展.
目的 探討清晨血壓高峰與頸動脈粥樣硬化的關繫.方法 97例輕、中度原髮性高血壓患者行24h動態血壓鑑測,併根據鑑測結果將之分為存在清晨血壓高峰組(MP+組,31例)和無清晨血壓高峰組(MP-組,66例).所有患者經綵色多普勒超聲檢測頸動脈內膜-中層厚度(IMT)和粥樣硬化斑塊的髮生情況,觀察清晨血壓高峰與頸動脈IMT和動脈粥樣硬化斑塊髮生率的相關性.結果 MP+組患者頸總動脈(CCA)、頸總動脈分扠處(CAB)和頸內動脈(ICA)的IMT均高于MP-組[(1.02±0.36)ram比(0.86±0.22)mm、(1.14±0.39)mm比(0.96±0.26)mm和(0.94±0.30)mm比(0.82±0.18)mln,P<0.05].MP+組頸動脈粥樣硬化斑塊的髮生率為64.5%(20/31),MP-組為42.4%(28/66),兩組比較差異有統計學意義(P<0.05).結論 清晨血壓高峰與頸動脈粥樣硬化相關,清晨血壓高峰可加速動脈粥樣硬化的形成和髮展.
목적 탐토청신혈압고봉여경동맥죽양경화적관계.방법 97례경、중도원발성고혈압환자행24h동태혈압감측,병근거감측결과장지분위존재청신혈압고봉조(MP+조,31례)화무청신혈압고봉조(MP-조,66례).소유환자경채색다보륵초성검측경동맥내막-중층후도(IMT)화죽양경화반괴적발생정황,관찰청신혈압고봉여경동맥IMT화동맥죽양경화반괴발생솔적상관성.결과 MP+조환자경총동맥(CCA)、경총동맥분차처(CAB)화경내동맥(ICA)적IMT균고우MP-조[(1.02±0.36)ram비(0.86±0.22)mm、(1.14±0.39)mm비(0.96±0.26)mm화(0.94±0.30)mm비(0.82±0.18)mln,P<0.05].MP+조경동맥죽양경화반괴적발생솔위64.5%(20/31),MP-조위42.4%(28/66),량조비교차이유통계학의의(P<0.05).결론 청신혈압고봉여경동맥죽양경화상관,청신혈압고봉가가속동맥죽양경화적형성화발전.
Objective To investigate the relativity between morning blood pressure surge (MBPS) and carotid atheresclerosis. Methods Noninvasive ambulatory blood pressure monitor (ABPM) was per-formed on 97 patients with the first and second stage of essential hypertension and according the ABPM re-suits, the patients were classified into MP+ group (31 cases) and MP-group (66 cases). In the meantime, the carotid intima-media thickness (IMT) and the carotid atheresclerotic plaque was examined by the color Doppler ultrasound. The relationship among MBPS, carotid atherosclerotic plaque and IMT was analyzed.Results The IMT of common carotid artery (CCA), carotid artery bifurcation (CAB)and internal carotid artery (ICA) in MP+ group was significantly higher than that in MP- group [ (1.02±0.36)mm vs (0.86±0.22) mm, (1.14±0.39 ) mm vs(0.96±0.26) mm, (0.94±0.30 )mm vs ( 0.82±0.18 mm ), P<0.05 ]. The ratio of carotid atherosclerotie plaque in MP+ group was significantly higher than that in MP- group (64.5% vs 42.4%,P<0.05). Conclusions The MBPS is related to carotid atheroselerotie plaque and the carotid IMT. The MBPS may accelerate the forming and developing of atherosclerosis.
