中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2008年
6期
367-369
,共3页
李蓓%赵铱民%杨聚才%韩颖%董智伟
李蓓%趙銥民%楊聚纔%韓穎%董智偉
리배%조의민%양취재%한영%동지위
弹性聚硅酮类%念珠菌,白色%纳米结构%二氧化钛
彈性聚硅酮類%唸珠菌,白色%納米結構%二氧化鈦
탄성취규동류%념주균,백색%납미결구%이양화태
Silicone elastomers%Candida albicans%Nanostructures%Titanium dioxide
目的 通过研究纳米二氧化钛对硅橡胶体外抗白色念珠菌性能的影响,探讨用纳米二氧化钛改善硅橡胶抗白色念珠菌性能的可靠性.方法 硅橡胶中加入质量分数分别为0.5%、1.0%、1.5%、2.0%的纳米二氧化钛抗菌剂,分别记为A、B、C、D组,对照组硅橡胶不加纳米二氧化钛,采用薄膜密着法在光照和无光照条件下测定各组硅橡胶对白色念珠菌的抗菌作用.结果 光照条件下,A、B、C、D组菌落数[分别为(439.0±21.9)CFU、(289.3±7.8)CFU、(173.0±7.6)CFU、(86.7±3.9)CFU]与对照组[(597.3±5.5)CFU]的差异均有统计学意义(P<0.05);非光照条件下,A、B、C、D组菌落数[分别为(543.7±22.8)CFU、(478.0±17.0)CFU、(422.7±21.8)CFU、(283.0±12.1)CFU]与对照组[(611.3±10.0)CFU]的差异均有统计学意义(P<0.05).D组抗菌性能最好,无光照条件下,抑菌率为53.7%;光照条件下,抑菌率可达85.9%.结论 添加了纳米二氧化钛抗菌剂的硅橡胶在光照和无光照条件下均能抑制白色念珠菌生长,随着纳米二氧化钛质量分数的增加,硅橡胶抑菌效果增强.纳米二氧化钛质量分数相同时,光照下硅橡胶的抑菌性比无光照强.
目的 通過研究納米二氧化鈦對硅橡膠體外抗白色唸珠菌性能的影響,探討用納米二氧化鈦改善硅橡膠抗白色唸珠菌性能的可靠性.方法 硅橡膠中加入質量分數分彆為0.5%、1.0%、1.5%、2.0%的納米二氧化鈦抗菌劑,分彆記為A、B、C、D組,對照組硅橡膠不加納米二氧化鈦,採用薄膜密著法在光照和無光照條件下測定各組硅橡膠對白色唸珠菌的抗菌作用.結果 光照條件下,A、B、C、D組菌落數[分彆為(439.0±21.9)CFU、(289.3±7.8)CFU、(173.0±7.6)CFU、(86.7±3.9)CFU]與對照組[(597.3±5.5)CFU]的差異均有統計學意義(P<0.05);非光照條件下,A、B、C、D組菌落數[分彆為(543.7±22.8)CFU、(478.0±17.0)CFU、(422.7±21.8)CFU、(283.0±12.1)CFU]與對照組[(611.3±10.0)CFU]的差異均有統計學意義(P<0.05).D組抗菌性能最好,無光照條件下,抑菌率為53.7%;光照條件下,抑菌率可達85.9%.結論 添加瞭納米二氧化鈦抗菌劑的硅橡膠在光照和無光照條件下均能抑製白色唸珠菌生長,隨著納米二氧化鈦質量分數的增加,硅橡膠抑菌效果增彊.納米二氧化鈦質量分數相同時,光照下硅橡膠的抑菌性比無光照彊.
목적 통과연구납미이양화태대규상효체외항백색념주균성능적영향,탐토용납미이양화태개선규상효항백색념주균성능적가고성.방법 규상효중가입질량분수분별위0.5%、1.0%、1.5%、2.0%적납미이양화태항균제,분별기위A、B、C、D조,대조조규상효불가납미이양화태,채용박막밀착법재광조화무광조조건하측정각조규상효대백색념주균적항균작용.결과 광조조건하,A、B、C、D조균락수[분별위(439.0±21.9)CFU、(289.3±7.8)CFU、(173.0±7.6)CFU、(86.7±3.9)CFU]여대조조[(597.3±5.5)CFU]적차이균유통계학의의(P<0.05);비광조조건하,A、B、C、D조균락수[분별위(543.7±22.8)CFU、(478.0±17.0)CFU、(422.7±21.8)CFU、(283.0±12.1)CFU]여대조조[(611.3±10.0)CFU]적차이균유통계학의의(P<0.05).D조항균성능최호,무광조조건하,억균솔위53.7%;광조조건하,억균솔가체85.9%.결론 첨가료납미이양화태항균제적규상효재광조화무광조조건하균능억제백색념주균생장,수착납미이양화태질량분수적증가,규상효억균효과증강.납미이양화태질량분수상동시,광조하규상효적억균성비무광조강.
Objective To study the antibacterial effect against Candida albicans of the A-2186 silicone elastomer containing nano-TiO2 in vitro. Methods Antibacterial agent of nano-TiO2 was added into A-2186 silicone elastomer with incorporating percentages of 0.5% , 1.0%, 1.5%, and 2. 0% (W/W).There was no nano-TiO2 in the control group. The antibacterial effect of the A-2186 silicone elastomer was determined using the film contact method with lighting and without lighting. Results Either with lighting or without lighting, there were significances between the experiment groups and the control group ( P < 0. 05 ).When the incorporating percent was 2. 0%, the inhibitory effect was the best among the experiment groups.Without lighting, the inhibitory rate was 53.7% and with lighting, the inhibitory rate was 85.9%.Conclusions The A-2186 silicone elastomer containing nano-TiO2 has antibacterial properties against Candida albicans, which enhances with increases of nano-TiO2 percent in the material. With the same incorporating percentage, the antibacterial effect with lighting is better than that without lighting.
