国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2012年
2期
125-129
,共5页
孔伟%王新%王海峰%张永红%王平%邢成名
孔偉%王新%王海峰%張永紅%王平%邢成名
공위%왕신%왕해봉%장영홍%왕평%형성명
高血压%认知障碍%危险因素%神经心理学测验%老年人
高血壓%認知障礙%危險因素%神經心理學測驗%老年人
고혈압%인지장애%위험인소%신경심이학측험%노년인
Hypertension%Cognition Disorders%Risk Factors%Neuropsychological Tests%Aged
目的 探讨高血压和其他血管危险因素与轻度认知损害及其亚型之间的关系.方法 收集2011年4月至2011年9月就诊于青岛4家市级医院神经科的门诊及住院患者297例,制定统一的青岛市医院神经科认知损害现状调查表,调查轻度认知损害及其亚型的危险因素.结果 单变量分析显示,低受教育年限[优势比(odds ratio,OR)0.239,95％可信区间(confidence interval,CI)0.129～0.442;P=0.000]、高血压(OR 1.928,95％CI1.107～3.358;P =0.019)和高脂血症(OR1.812,95％ CI1.041 ～3.155;P=0.034)均为轻度认知损害的危险因素；多变量logistic回归分析显示,低教育水平( OR0.807,95％ CI0.742 ～0.878；P=0.000)和高血压(OR1.788,95％ CI1.004～3.146;P =0.048)为轻度认知损害的独立危险因素,且高血压为非遗忘型轻度认知损害的独立危险因素(OR2.091,95％ CI1.030 ～4.242;P=0.041),以视空间和执行能力受损为主(P=0.026).结论 高血压为轻度认知损害及其亚型非遗忘型轻度认知损害的独立危险因素,且以执行能力受损为主.
目的 探討高血壓和其他血管危險因素與輕度認知損害及其亞型之間的關繫.方法 收集2011年4月至2011年9月就診于青島4傢市級醫院神經科的門診及住院患者297例,製定統一的青島市醫院神經科認知損害現狀調查錶,調查輕度認知損害及其亞型的危險因素.結果 單變量分析顯示,低受教育年限[優勢比(odds ratio,OR)0.239,95％可信區間(confidence interval,CI)0.129～0.442;P=0.000]、高血壓(OR 1.928,95％CI1.107～3.358;P =0.019)和高脂血癥(OR1.812,95％ CI1.041 ～3.155;P=0.034)均為輕度認知損害的危險因素；多變量logistic迴歸分析顯示,低教育水平( OR0.807,95％ CI0.742 ～0.878；P=0.000)和高血壓(OR1.788,95％ CI1.004～3.146;P =0.048)為輕度認知損害的獨立危險因素,且高血壓為非遺忘型輕度認知損害的獨立危險因素(OR2.091,95％ CI1.030 ～4.242;P=0.041),以視空間和執行能力受損為主(P=0.026).結論 高血壓為輕度認知損害及其亞型非遺忘型輕度認知損害的獨立危險因素,且以執行能力受損為主.
목적 탐토고혈압화기타혈관위험인소여경도인지손해급기아형지간적관계.방법 수집2011년4월지2011년9월취진우청도4가시급의원신경과적문진급주원환자297례,제정통일적청도시의원신경과인지손해현상조사표,조사경도인지손해급기아형적위험인소.결과 단변량분석현시,저수교육년한[우세비(odds ratio,OR)0.239,95％가신구간(confidence interval,CI)0.129～0.442;P=0.000]、고혈압(OR 1.928,95％CI1.107～3.358;P =0.019)화고지혈증(OR1.812,95％ CI1.041 ～3.155;P=0.034)균위경도인지손해적위험인소；다변량logistic회귀분석현시,저교육수평( OR0.807,95％ CI0.742 ～0.878；P=0.000)화고혈압(OR1.788,95％ CI1.004～3.146;P =0.048)위경도인지손해적독립위험인소,차고혈압위비유망형경도인지손해적독립위험인소(OR2.091,95％ CI1.030 ～4.242;P=0.041),이시공간화집행능력수손위주(P=0.026).결론 고혈압위경도인지손해급기아형비유망형경도인지손해적독립위험인소,차이집행능력수손위주.
Objective To investigate the relationship between hypertension,other vascular risk factors and mild cognitive impairment and its subtype.Methods A total of 297 outpatients and inpatients were collected from the Departments of Neurology in 4 municipal hospitals in Qingdao from April 2011 to September 2011.The unified questionnaires of cognitive impairment status in the departments of neurology in Qingdao city were developed.The risk factors for mild cognitive impairment and its subtype were investigated.Results Univariate analysis showed that low levels of education (odds ratio [ OR] 0.239,95％ confidence interval [ CI] 0.129 -0.442; P =0.000),hypertension (OR 1.928,95％ CI 1.107 - 3.358; P =0.019) and hyperlipidemia (OR 1.812,95％ CI 1.041 -3.155; P =0.034) were all the risk factors for mild cognitive impairment; Multivariate logistic regression analysis showed that low levels of education (OR 0.807,95％ CI 0.742 - 0.878; P =0.000) and hypertension (OR 1.788,95％ CI 1.004 -3.146; P =0.048 ) were the independent risk factors for mild cognitive impairment; and hypertension (OR 2.091,95％ CI 1.030 -4.242; P=0.041) was an independent risk factor for non-amnestic mild cognitive impairment,and was mainly impaired visuospatial and executive abilities (P =0.026).Conclusions Hypertension is an independent risk factor for mild cognitive impairment and its subtype-non-amnestic mild cognitive impairment,and it mainly impairs executive ability.
