CAJ | 학술논문

目前斑马鱼作为一种新的模式动物越来越受科学家们重视,因其与哺乳动物肾脏的发育及疾病的发生、发展存在很多相似之处,涉及的许多基因具有高度保守性,且结构简单、易于操作和观察,已被广泛应用于肾脏领域的研究.该文对斑马鱼作为一种模式生物在肾脏发育和肾脏疾病中的应用进行综述.
목전반마어작위일충신적모식동물월래월수과학가문중시,인기여포유동물신장적발육급질병적발생、발전존재흔다상사지처,섭급적허다기인구유고도보수성,차결구간단、역우조작화관찰,이피엄범응용우신장영역적연구.해문대반마어작위일충모식생물재신장발육화신장질병중적응용진행종술.
As a kind of new model organisms,zebrafish attracts more and more scientists'attention.Because the nephrogenesis and much of kidney disease in zebrafish are similar to those in mammalian,many genes in both kidneys are conserved,and zebrafish has the more simple pronephron,which is convenient to operation and observation.The fish pronephron has been generally applied to study the development and disease of mammalian kidney.This review will focus on recent progress in applying the zebrafish pronephrons to issues of human health and development.