CAJ | 학술논문

目的探讨头孢曲松钠引发尿路结石的理化性质. 方法 2012年4月收检头孢曲松钠引发的儿童尿路结石2例.其中1例于2012年3月行头孢曲松钠治疗,过程中突发尿路结石,经治疗后自行排出沙粒状结石.另一例于2012年4月行头孢曲松钠治疗5d后突发下腹痛、呕吐,B超检查示右输尿管结石,KUB检查未见结石影,CT检查示右输尿管上段结石伴积水.保守治疗3d后结石排出,复查B超和IVU未见结石影.采用红外光谱、扫描电子显微镜及能谱仪分析2例尿路结石的成分. 结果 2例尿路结石样本均由头孢曲松和钙离子构成,摩尔比为1∶1. 结论头孢曲松钠可引发尿石症,该结石具有X线下不显影的影像学特征,尿路结石成分为头孢曲松钙盐.
목적 탐토두포곡송납인발뇨로결석적이화성질. 방법 2012년4월수검두포곡송납인발적인동뇨로결석2례.기중1례우2012년3월행두포곡송납치료,과정중돌발뇨로결석,경치료후자행배출사립상결석.령일례우2012년4월행두포곡송납치료5d후돌발하복통、구토,B초검사시우수뇨관결석,KUB검사미견결석영,CT검사시우수뇨관상단결석반적수.보수치료3d후결석배출,복사B초화IVU미견결석영.채용홍외광보、소묘전자현미경급능보의분석2례뇨로결석적성분. 결과 2례뇨로결석양본균유두포곡송화개리자구성,마이비위1∶1. 결론 두포곡송납가인발뇨석증,해결석구유X선하불현영적영상학특정,뇨로결석성분위두포곡송개염.
Objective To investigate the physicochemical characteristics of urinary stone induced by ceftriaxone.Methods Two children cefriaxone-associated urinary stone samples were received for component analysis in our hospital in April 2012,of which one was from a boy whose clinical data was not available,and the other was from a boy who suffered acute lower abdominal pain and vomiting after treatment with ceftriaxone for 5 d in early April.Ultrasound demonstrated a stone in his right upper ureter.Computed tomography showed right upper ureteral stone,which was radiolucent on plain abdominal radiograph.After a conservative treatment for 3 d,the stone in right upper ureter was spontaneously passed,which was confirmed by the ultrasound and intravenous pyelography.The two received stone samples were analyzed by infrared spectroscopy,scanning electron microscopy and energy disperse spectroscopy for component analysis.Results The compositions of two stone samples were free ceftriaxone and calcium ions combined with a molar ratio of 1:1.Conclusions The ceftriaxone could induce urinary stone in children.This special stone has radiolueent imaging,and it is composed of calcium ceftriaxone salt.