CAJ | 학술논문

白细胞介素-15 (IL-15)是一种多功能的细胞因子,是T细胞、B细胞、自然杀伤(NK)细胞、淋巴因子激活杀伤(LAK)细胞等细胞活化因子及诱导分泌细胞因子,有刺激造血干细胞增殖分化、增强免疫和抗肿瘤等作用.IL-15具有与白细胞介素-2(IL-2)类似的结构和功能,但许多活性作用强于IL-2,其与肿瘤的发生发展密切相关,且在肿瘤生物治疗方面有广阔的应用前景.
백세포개소-15 (IL-15)시일충다공능적세포인자,시T세포、B세포、자연살상(NK)세포、림파인자격활살상(LAK)세포등세포활화인자급유도분비세포인자,유자격조혈간세포증식분화、증강면역화항종류등작용.IL-15구유여백세포개소-2(IL-2)유사적결구화공능,단허다활성작용강우IL-2,기여종류적발생발전밀절상관,차재종류생물치료방면유엄활적응용전경.
Interleukin-15 is a multffunctional cytokine,which are the activating and induction factors of the T-cell,B-cell,NK-cell and lymphokine-activated killer cell (LAK).It can stimulate hematopoietic stem cell proliferation and differentiation,enhance immunity and has anti-tumor effects.IL-15 and IL-2 have similar structures and functions,but many activating effects of IL-15 are stronger than the other's.IL-15 is closely related to tumor development,and has broad application prospects in biological therapy of cancer.