CAJ | 학술논문

目的探讨静脉注射毒品所致感染性心内膜炎的外科治疗经验.方法 17例患者静脉注射毒品史2～10年,均有心脏瓣膜赘生物;其中三尖瓣赘生物并关闭不全16例,二尖瓣赘生物并关闭不全合并室间隔缺损1例,术前血培养阳性8例.三尖瓣置换术8例,三尖瓣成形术8例,二尖瓣置换同期室间隔缺损修补术1例.术后平均随访(44.7 ±19.1)月.结果全部患者治愈出院,心功能明显改善,随访期间抗凝不当致大咯血1例,三尖瓣重度返流1例.结论外科手术修复受累瓣膜或置换瓣膜是治疗静脉吸毒性感染性心内膜炎的有效手段.
목적 탐토정맥주사독품소치감염성심내막염적외과치료경험.방법 17례환자정맥주사독품사2～10년,균유심장판막췌생물;기중삼첨판췌생물병관폐불전16례,이첨판췌생물병관폐불전합병실간격결손1례,술전혈배양양성8례.삼첨판치환술8례,삼첨판성형술8례,이첨판치환동기실간격결손수보술1례.술후평균수방(44.7 ±19.1)월.결과 전부환자치유출원,심공능명현개선,수방기간항응불당치대각혈1례,삼첨판중도반류1례.결론 외과수술수복수루판막혹치환판막시치료정맥흡독성감염성심내막염적유효수단.
Objective To summarize the experience of surgical treatment of venous drug-induced infective endocarditis(IE). Methods The 17 cases of drug-induced IE were found to have valvular vegetations,16 patients had involvement of tricuspid valve, 1 mitral valve associated with ventrieular septal defect. Preoperative blood culture was positive in 8 patients. The operations included tricuspid valve repair (6 cases),tricuspid valve replacement(8 cases), mitral valve replacement and VSD closure(1 cases). Results All patients were alive and discharges. After follow-up of 6 months to 6 years, 1 case had severd tricuspid alve regurgitation, 1 had haemoptysis because of incorrect anticoagulation. Conclusions This study indicated surgical intervention is effective treatment of venous drug-induced infective endocarditis.