CAJ | 학술논문

目的分析近年来珠江三角洲地区泌尿系结石患者的结石组分和尿微晶性质,期望为尿石症的预防和治疗提供启示.方法采用X射线衍射(XRD)和傅立叶变换红外光谱(FT-IR)对随机抽样的30例结石样本进行联合分析;同时采用纳米粒度仪研究尿石症患者尿液中纳米微晶的平均粒径、粒度分布、多分散系数(PDI)和Zeta电位等性质,并与健康对照者进行比较.结果珠江三角洲地区泌尿系结石以草酸钙结石为主,占76.6%;其次为尿酸结石,占16.7%;磷酸钙结石约占6.7%.尿石症患者尿微晶的平均粒径、粒度分布、多分散系数(PDI)和Zeta电位与健康对照者比较差异有统计学意义.结论草酸钙、尿酸和磷酸钙构成了珠江三角洲地区泌尿系结石的主要成分;尿石症患者和健康对照者尿微晶在平均粒径、粒度分布、多分散系数(PDI)和Zeta电位等方面性质的差异使得正常人不容易得结石.
목적 분석근년래주강삼각주지구비뇨계결석환자적결석조분화뇨미정성질,기망위뇨석증적예방화치료제공계시.방법 채용X사선연사(XRD)화부립협변환홍외광보(FT-IR)대수궤추양적30례결석양본진행연합분석;동시채용납미립도의연구뇨석증환자뇨액중납미미정적평균립경、립도분포、다분산계수(PDI)화Zeta전위등성질,병여건강대조자진행비교.결과 주강삼각주지구비뇨계결석이초산개결석위주,점76.6%;기차위뇨산결석,점16.7%;린산개결석약점6.7%.뇨석증환자뇨미정적평균립경、립도분포、다분산계수(PDI)화Zeta전위여건강대조자비교차이유통계학의의.결론 초산개、뇨산화린산개구성료주강삼각주지구비뇨계결석적주요성분;뇨석증환자화건강대조자뇨미정재평균립경、립도분포、다분산계수(PDI)화Zeta전위등방면성질적차이사득정상인불용역득결석.
Objective To seek the methods in the prevention and treatment of urinary stones, stone composition and the property of urinary crystallites of lithogenic patients in Pearl River Delta area in recent years were analyzed. Methods Thirty random stone samples were investigated by XRD and FT-IR method. The mean diameter, particle size distribution, polydispersity index(PDI) and Zeta potential of urinary nanocrystallites in lithogenic urines were investigated in nanoparticle size analyzer and were compared with those in healthy subjects. Results Calcium oxalate stone was the main urinary stones in Pearl River Delta area, which accounting for 76.6%, and followed by uric acid and calcium phosphate stones, which accounting for 16.7% and 6.7%, respectively. In urinary nanocrystallites, there was significant difference between lithogenic subjects and healthy subjects in mean diameter, particle size distribution, polydispersity index (PDI) and Zeta potential. Conclusion Calcium oxalate, uric acid, and calcium phosphate were the main constituents of urinary stones in Pearl River Delta area. The right mean diameter, particle size distribution, PDI and Zeta potential of urinary nanocrystallites prevent healthy subjects from lithangiuria.