CAJ | 학술논문

目的探讨米非司酮在子宫切口瘢痕妊娠(CSP)治疗中的独立效果. 方法回顾分析2003年1月-2009年12月我院确诊为CSP并接受米非司酮治疗的13例患者的病历资料,以治疗前后血绒毛膜促性腺激素(β-hCG)水平变化等分析米非司酮在CSP治疗中的独立作用. 结果 5例使用米非司酮作为负压吸引术后的后续治疗,血β-hCG均明显下降;6例使用米非司酮作为氨甲喋呤化疗后的后续治疗,2例患者血β-hCG明显下降;2例使用米非司酮作为初始治疗,1例患者血β-hCG明显下降. 结论对接受负压吸引术后血β-hCG持续不下降的CSP患者,米非司酮作为后续治疗的效果明显;对接受氨甲喋呤治疗后血β-hCG下降不明显的CSP患者,米非司酮作为后续治疗效果多数不明显.
목적 탐토미비사동재자궁절구반흔임신(CSP)치료중적독립효과. 방법 회고분석2003년1월-2009년12월아원학진위CSP병접수미비사동치료적13례환자적병력자료,이치료전후혈융모막촉성선격소(β-hCG)수평변화등분석미비사동재CSP치료중적독립작용. 결과 5례사용미비사동작위부압흡인술후적후속치료,혈β-hCG균명현하강;6례사용미비사동작위안갑첩령화료후적후속치료,2례환자혈β-hCG명현하강;2례사용미비사동작위초시치료,1례환자혈β-hCG명현하강. 결론 대접수부압흡인술후혈β-hCG지속불하강적CSP환자,미비사동작위후속치료적효과명현;대접수안갑첩령치료후혈β-hCG하강불명현적CSP환자,미비사동작위후속치료효과다수불명현.
Objective To evaluate the independent effectiveness of mifepristone in the management of cesarean scar pregnancy (CSP).Methods The clinical data of 13 patients with CSP treated with mifepristone in our hospital from January 2003 to December 2009 were retrospectively analyzed.Change of serumβ-hCG level was used to estimate the independent role of mifepristone.Results Five patients were treated with mifepristone subsequently to suction curettage and the serum β-hCG of all these patients remarkably decreased.Six patients were treated with mifepristone subsequently to methotrexate;the serum β-hCG remarkably decrease in two of them.Two patients were treated with mifepristone initially and the serum β-hCG remarkably decreased in one patient.Conclusion Mifepristone is effective when applied as subsequent treatment in CSP patients whose β-hCG does not decrease after suction curettage treatment;however,its role may be limited when used as subsequent treatment following methotrexate.