CAJ | 학술논문

目的观察胶原基纳米骨(nHAC)加自体骨修复颌骨缺损的临床效果.方法选择颌骨缺损需植骨者,随机分为3组,分别填入nHAC加自体骨(63例),骨诱导活性材料(OAM)(44例)以及单纯nHAC(57例)3组不同植骨材料.术后1、2、3、 4、6、8、12个月复诊,对病损部位进行临床及X线检查,观察新骨形成情况.结果 nHAC加自体骨、OAM、nHAC充填修复颌骨缺损之间疗效无显著差异(P>0.05),X线显示nHAC加自体骨、OAM成骨速度早于单纯nHAC.结论 nHAC加自体骨修复颌骨缺损是一种可行的方法,可以提高骨缺损修复的效果.
목적 관찰효원기납미골(nHAC)가자체골수복합골결손적림상효과.방법 선택합골결손수식골자,수궤분위3조,분별전입nHAC가자체골(63례),골유도활성재료(OAM)(44례)이급단순nHAC(57례)3조불동식골재료.술후1、2、3、 4、6、8、12개월복진,대병손부위진행림상급X선검사,관찰신골형성정황.결과 nHAC가자체골、OAM、nHAC충전수복합골결손지간료효무현저차이(P>0.05),X선현시nHAC가자체골、OAM성골속도조우단순nHAC.결론 nHAC가자체골수복합골결손시일충가행적방법,가이제고골결손수복적효과.
Objective To study clinical effect of the mixture of nano-hydroxyapative/collagen composite ( nHAC) and autogenous chip bone in repairing jaw defects. Methods Jaw defects in need of transplanting bone were selected and randomly divided into three groups. Three methods ( the mixture of nHAC and autogenous chip bone(63 cases) , osteoinduction active material(OAM)(44 cases) , nHAC (57cases) were used to repair the jaw defects. After 1, 2,3 ,4, 6, 8 and 12 months, all cases were checked the condition of new bone formed and calcified by X-ray and clinical examination. Results There were no significant differences of the mixture of nHAC and autogenous chip bone, 0AM, nHAC in repairing jaw defects(P > 0. 05 ). New bone formed and calcified earlier in the mixture of nHAC and autogenous chip bone and 0AM than that in nHAC. Conclusion It is feasible to repair jaw defects using the mixture of nHAC and autogenous chip bone. The mixture may promote the reparation of bone defects.