中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
7期
899-900
,共2页
氨酚羟考酮%关节成形术,置换,髋%镇痛
氨酚羥攷酮%關節成形術,置換,髖%鎮痛
안분간고동%관절성형술,치환,관%진통
Oxycodone-acetaminophen%Arthroplasty,Replacement,Hop%Analgesia
目的 观察氨酚羟考酮对全髋关节置换术患者术后镇痛的效果.方法 选择全髋关节置换术后患者93例,随机分为两组:氨酚羟考酮组(观察组)和安慰剂组(对照组).氨酚羟考酮组:术前8 h开始口服氨酚羟考酮1片,2次/d,连续使用3 d;安慰剂组:选用维生素E胶丸作为安慰剂,服用方法同氨酚羟考酮组.术后6 h、24 h、48 h及72 h各做一次VAS评分并观察服药后的不良反应情况.结果 观察组患者在术后6 h、24 h、48 h及72 h的VAS评分明显低于对照组患者,差异均有统计学意义(均P＜0.05).观察组仅有轻微的恶心呕吐、嗜睡、厌食等药物不良反应,两组差异均无统计学意义(均P＞0.05).结论 氨酚羟考酮对全髋关节置换术后的患者具有明显的镇痛效果,且无明显不良反应.
目的 觀察氨酚羥攷酮對全髖關節置換術患者術後鎮痛的效果.方法 選擇全髖關節置換術後患者93例,隨機分為兩組:氨酚羥攷酮組(觀察組)和安慰劑組(對照組).氨酚羥攷酮組:術前8 h開始口服氨酚羥攷酮1片,2次/d,連續使用3 d;安慰劑組:選用維生素E膠汍作為安慰劑,服用方法同氨酚羥攷酮組.術後6 h、24 h、48 h及72 h各做一次VAS評分併觀察服藥後的不良反應情況.結果 觀察組患者在術後6 h、24 h、48 h及72 h的VAS評分明顯低于對照組患者,差異均有統計學意義(均P＜0.05).觀察組僅有輕微的噁心嘔吐、嗜睡、厭食等藥物不良反應,兩組差異均無統計學意義(均P＞0.05).結論 氨酚羥攷酮對全髖關節置換術後的患者具有明顯的鎮痛效果,且無明顯不良反應.
목적 관찰안분간고동대전관관절치환술환자술후진통적효과.방법 선택전관관절치환술후환자93례,수궤분위량조:안분간고동조(관찰조)화안위제조(대조조).안분간고동조:술전8 h개시구복안분간고동1편,2차/d,련속사용3 d;안위제조:선용유생소E효환작위안위제,복용방법동안분간고동조.술후6 h、24 h、48 h급72 h각주일차VAS평분병관찰복약후적불량반응정황.결과 관찰조환자재술후6 h、24 h、48 h급72 h적VAS평분명현저우대조조환자,차이균유통계학의의(균P＜0.05).관찰조부유경미적악심구토、기수、염식등약물불량반응,량조차이균무통계학의의(균P＞0.05).결론 안분간고동대전관관절치환술후적환자구유명현적진통효과,차무명현불량반응.
Objective To investigate the analgesic effect of oxycodone-acetaminophen tablet on total hip replacement(THR).Methods 93 patients were chosen and randomly divided into two groups:oxycodone-acetaminophen group(experimental group)and placebo group(control group).Analgesic effect of postoperation and adverse effects were observed.Results Compared with the control group,analgesic effect of postoperative 6h,24h,48h and 72h in experimental group had statistically significant difference(all P＜0.05).Compared with the control group,adverse effect in experimental group had no statistically significant difference(all P＞0.05).Conclusion Oxycodoneacetaminophen in THR postoperative patients had obvious analgesic effect and had no obvious side effects.
