CAJ | 학술논문

目的探讨原发性上尿路淋巴上皮样癌的临床表现、病理特点、治疗和预后. 方法原发性输尿管淋巴上皮样癌患者1例.女,81岁.间断无痛性全程肉眼血尿1个月就诊.CT尿路造影提示左输尿管盆腔段腔内可见长约2.5 cm类圆形软组织密度影.行腹腔镜下左输尿管癌根治术. 结果大体标本:纵行打开输尿管,距输尿管远端3.5 cm处见2.5 cm×2.0 cm隆起肿物,切面灰白,质稍硬,实性.镜检:肿瘤细胞呈巢状分布,体积较大,胞质丰富,核大,圆形,空泡状,核仁明显,间质内大量小淋巴细胞浸润.病理诊断:输尿管淋巴上皮样癌,浸及深肌层,病理分期pT2N0M0.原位杂交技术EBER为阴性.随诊3个月未见肿瘤复发及转移. 结论原发性上尿路淋巴上皮样癌罕见,需经病理组织学检查确诊.根治手术为主要治疗手段,预后优于其他类型尿路上皮癌.
목적 탐토원발성상뇨로림파상피양암적림상표현、병리특점、치료화예후. 방법 원발성수뇨관림파상피양암환자1례.녀,81세.간단무통성전정육안혈뇨1개월취진.CT뇨로조영제시좌수뇨관분강단강내가견장약2.5 cm류원형연조직밀도영.행복강경하좌수뇨관암근치술. 결과대체표본:종행타개수뇨관,거수뇨관원단3.5 cm처견2.5 cm×2.0 cm륭기종물,절면회백,질초경,실성.경검:종류세포정소상분포,체적교대,포질봉부,핵대,원형,공포상,핵인명현,간질내대량소림파세포침윤.병리진단:수뇨관림파상피양암,침급심기층,병리분기pT2N0M0.원위잡교기술EBER위음성.수진3개월미견종류복발급전이. 결론원발성상뇨로림파상피양암한견,수경병리조직학검사학진.근치수술위주요치료수단,예후우우기타류형뇨로상피암.
Objective To investigate the clinical presentations,pathologic features,treatment and prognosis of lymphoepithelioma-like carcinoma(LELC)in the upper urinary tract. Methods A case with LELC of the ureter was retrospectively analyzed.A 81-year-old female patient was hospitalized because of gross hematuria for 1 month. CTU demonstrated a 2.5cm tumor in the left ureter.Radical nephroureterectomy was performed laparoscopically. Results Pathologic findings showed invasive poorly differentiated carcinoma in a prominent lymphocytic background.The diagnosis was LELC of the ureter.Epstein-Barr virus in situ hybridization was negative.No disease progression was noted at 3-month foUow-up. Conclusions LELC of the upper urinary tract is rare.All the cases are diagnosed pathologically.The disease eould be treated with radical surgery.Although the differentiation of the tumour cells is poor,the prognosis of pure subtypes seems to be better than that of other types of urothelial carcinoma.