CAJ | 학술논문

目的了解贵阳城区健康成人男性维生素D营养状况.方法抽取贵阳市主城区一社区,在该社区中按年龄段进行分层抽样,抽取20～79岁健康成人男性700名.2009年11月至2010年1月进行问卷调查,同时采集清晨空腹静脉血,分离血清测定血清25-羟维生素D[25(OH)D]水平.结果资料齐全的627名贵阳城区健康成人男性血清25(OH)D水平为(21±10) μg/L；维生素D缺乏[25(OH)D ＜20 μg/L]、不足[20 μg/L≤25 (OH)D＜30 μg/L]及正常者[25 (OH)D≥30.0μg/L]分别为315例(50.2％)、202例(32.2％)及110例(17.6％)；青年(20～ 39岁)、中年(40～59岁)及老年(60～ 79岁)组血清25(OH)D水平正常者分别为72、152、105例,血清25(OH)D水平依次为(18±10) μg/L、(24±10)μg/L及(22±8)μg/L；不吸烟组较吸烟组具有更高25(OH)D水平(22 μg/L比20μg/L,P=0.003)；调查对象中受教育年限≤6年、7～9年、10～12年及≥13年组血清25(OH)D水平分别为(24±10)μg/L、(23±10) μg/L、( 22±9)μg/L及(18±9)μg/L,25(OH)D水平与受教育年限呈负相关(r=-0.138,P=0.000).结论贵阳城区健康成人男性维生素D缺乏现象普遍,尤其见于青年人、吸烟及高学历者.
목적 료해귀양성구건강성인남성유생소D영양상황.방법 추취귀양시주성구일사구,재해사구중안년령단진행분층추양,추취20～79세건강성인남성700명.2009년11월지2010년1월진행문권조사,동시채집청신공복정맥혈,분리혈청측정혈청25-간유생소D[25(OH)D]수평.결과 자료제전적627명귀양성구건강성인남성혈청25(OH)D수평위(21±10) μg/L；유생소D결핍[25(OH)D ＜20 μg/L]、불족[20 μg/L≤25 (OH)D＜30 μg/L]급정상자[25 (OH)D≥30.0μg/L]분별위315례(50.2％)、202례(32.2％)급110례(17.6％)；청년(20～ 39세)、중년(40～59세)급노년(60～ 79세)조혈청25(OH)D수평정상자분별위72、152、105례,혈청25(OH)D수평의차위(18±10) μg/L、(24±10)μg/L급(22±8)μg/L；불흡연조교흡연조구유경고25(OH)D수평(22 μg/L비20μg/L,P=0.003)；조사대상중수교육년한≤6년、7～9년、10～12년급≥13년조혈청25(OH)D수평분별위(24±10)μg/L、(23±10) μg/L、( 22±9)μg/L급(18±9)μg/L,25(OH)D수평여수교육년한정부상관(r=-0.138,P=0.000).결론 귀양성구건강성인남성유생소D결핍현상보편,우기견우청년인、흡연급고학력자.
Objective To evaluate the vitamin D status of healthy adult males living in Guiyang.Methods A total of 700 healthy volunteers aged 20 - 79 years were selected randomly from a community in Guiyang by stratified sampling method.Questionnaires for living habits and fasting blood samples were collected in the morning from November 2009 to January 2010.The serum concentrations of 25-hydroxyvitamin D were measured by the DiaSorin radioimmunoassay kit.Results The mean levels of serum 25(OH)D was (21 ± 10) μg/L.And the percentages of vitamin D deficiency (25(OH)D ＜20 μg/L),insufficiency (20 μg/L ≤25 (OH) D ＜ 30 μg/L) and sufficiency (25 (OH) D ≥30.0 μg/L) were 315(50.2％ ),202 (32.2％ ) and 110 ( 17.6％ ) respectively.The concentrations of serum 25 (OH) D in young,middle-aged and old adults were (18 ± 10) μg/L,(24 ± 10) μg/L and (22 ± 8 )μg/L respectively.The serum level of 25 (OH)D was lower in the smokers than that in the non-smokers (20 μg/L vs 22 μg/L,P =0.003).The serum concentrations of 25 (OH) D were (24 ± 10) μg/L,(23 ± 10) μg/L,(22 ± 9 ) μg/L and (18 ± 9) μg/L in education level ( ≤6,7 - 9,10 - 12 and ≥ 10 years in school) respectively.Significant inverse correlations existed between the concentrations of serum 25 (OH) D and the education levels (r =-0.138,P =0.000).Condusion The prevalence of hypovitaminosis D is common in healthy adult males in Guiyang,especially among the youth,smokers and higher educated groups.