国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
15期
1176-1179
,共4页
邱志辉%伍颖欣%罗嘉莹%严惠婵
邱誌輝%伍穎訢%囉嘉瑩%嚴惠嬋
구지휘%오영흔%라가형%엄혜선
儿童%肥胖%阻塞性呼吸暂停%多导睡眠图
兒童%肥胖%阻塞性呼吸暫停%多導睡眠圖
인동%비반%조새성호흡잠정%다도수면도
Children%Obesity%Obstructive sleep apnea%Polysomnography
目的 成人肥胖与阻塞性呼吸暂停(OSA)的严重程度存在明显的正相关,但儿童肥胖与OSA的严重程度是否也存在正相关,目前结果并不一致.我们探讨儿童肥胖与OSA严重程度的关系以及分析不同体质量组儿童和青少年的多导睡眠图(PSG)的特点.方法 对235例疑为睡眠呼吸暂停面前来睡眠中心进行PSG检查的儿童和青少年(7～18岁)进行回顾性分析,根据体质量分为正常、超重和肥胖三组,比较不同组别之间的PSG结果以及肥胖与睡眠呼吸暂停低通气指数(AHI)和最低血氧饱和度相关性分析.结果 ①191例诊断为OSA,其中肥胖组有36例(18.8％),超重组有37例(19.4％),正常组有118例(61.8％)；②肥胖组的平均AHI[(19.10±24.60)次/h]明显大于超重组[(8.90±13.00)次/h]和正常组[(8.50±15.50)次/h],差异有统计学意义(P值均＜0.05)；③肥胖与AHI呈正相关(r =0.202),与低氧血症呈负相关(r=-0.219),P值均＜0.05.结论 儿童及青少年OSA发病与自身的肥胖存在密切相关.
目的 成人肥胖與阻塞性呼吸暫停(OSA)的嚴重程度存在明顯的正相關,但兒童肥胖與OSA的嚴重程度是否也存在正相關,目前結果併不一緻.我們探討兒童肥胖與OSA嚴重程度的關繫以及分析不同體質量組兒童和青少年的多導睡眠圖(PSG)的特點.方法 對235例疑為睡眠呼吸暫停麵前來睡眠中心進行PSG檢查的兒童和青少年(7～18歲)進行迴顧性分析,根據體質量分為正常、超重和肥胖三組,比較不同組彆之間的PSG結果以及肥胖與睡眠呼吸暫停低通氣指數(AHI)和最低血氧飽和度相關性分析.結果 ①191例診斷為OSA,其中肥胖組有36例(18.8％),超重組有37例(19.4％),正常組有118例(61.8％)；②肥胖組的平均AHI[(19.10±24.60)次/h]明顯大于超重組[(8.90±13.00)次/h]和正常組[(8.50±15.50)次/h],差異有統計學意義(P值均＜0.05)；③肥胖與AHI呈正相關(r =0.202),與低氧血癥呈負相關(r=-0.219),P值均＜0.05.結論 兒童及青少年OSA髮病與自身的肥胖存在密切相關.
목적 성인비반여조새성호흡잠정(OSA)적엄중정도존재명현적정상관,단인동비반여OSA적엄중정도시부야존재정상관,목전결과병불일치.아문탐토인동비반여OSA엄중정도적관계이급분석불동체질량조인동화청소년적다도수면도(PSG)적특점.방법 대235례의위수면호흡잠정면전래수면중심진행PSG검사적인동화청소년(7～18세)진행회고성분석,근거체질량분위정상、초중화비반삼조,비교불동조별지간적PSG결과이급비반여수면호흡잠정저통기지수(AHI)화최저혈양포화도상관성분석.결과 ①191례진단위OSA,기중비반조유36례(18.8％),초중조유37례(19.4％),정상조유118례(61.8％)；②비반조적평균AHI[(19.10±24.60)차/h]명현대우초중조[(8.90±13.00)차/h]화정상조[(8.50±15.50)차/h],차이유통계학의의(P치균＜0.05)；③비반여AHI정정상관(r =0.202),여저양혈증정부상관(r=-0.219),P치균＜0.05.결론 인동급청소년OSA발병여자신적비반존재밀절상관.
Objective The correlation between obesity and severity of obstructive sleep apnea (OSA) is well established in adults,but data are inconsistent in children.We explored the influence of obesity on the children and adolescent with OSA.Methods We retrospectively studied 235 children (aged 7-18 years)who were suspected to suffer from sleep apnea and were referred to our sleep center for overnight polysomnography (PSG).The subjects were divided into three groups based on their BMI Z score:normal group,overweight group and obesity group.PSG was compared among the different groups.The correlation between BMI Z score and apnea-hypopnea index (AHI) and lowest value of SaO2 (SaO2 nadir) during sleep was assessed.Results AHI was higher in obesity group [( 19.10±24.60) events/hour]than that in overweight group and normal group [(8.90± 13.00) events/hour,(8.50± 15.50) events/hour].BMI Z score was correlated with log-transfotmed AHI ( r =0.202,P ＜0.05) and SaO2 nadir( r =-0.219,P ＜0.05).Conclusions Degree of obesity as measured by BMI Z score is significantly related to severity of OSA as reflected by the AHI,although the correlation is mild.
