CAJ | 학술논문

目的探讨获得性免疫缺陷综合征(AIDS)合并巨细胞病毒(CMV)性视网膜炎患者的眼底改变特点及眼底荧光血管造影特征.方法已诊断为CMV性视网膜炎的AIDS患者共34例49只眼,进行常规视力、裂隙灯检查、眼底检查及荧光素眼底血管造影(FFA)检查,分析其眼底病变的临床特征.结果 29只眼视网膜上见大片融合性黄白色坏死灶,边界不清,伴视网膜出血及血管炎改变；FFA晚期病灶区域弥漫性荧光素渗漏.12只眼周边部视网膜颗粒状坏死灶,边界欠清,未见明显视网膜出血、渗出及血管管壁改变；FFA显示病灶区域强荧光,晚期荧光素渗漏.4只眼视网膜前见大片灰白色增殖膜；4只眼继发视网膜脱离.结论 CMV性视网膜炎主要表现为进行性坏死性的视网膜炎,伴出血及血管炎.
목적 탐토획득성면역결함종합정(AIDS)합병거세포병독(CMV)성시망막염환자적안저개변특점급안저형광혈관조영특정.방법 이진단위CMV성시망막염적AIDS환자공34례49지안,진행상규시력、렬극등검사、안저검사급형광소안저혈관조영(FFA)검사,분석기안저병변적림상특정.결과 29지안시망막상견대편융합성황백색배사조,변계불청,반시망막출혈급혈관염개변；FFA만기병조구역미만성형광소삼루.12지안주변부시망막과립상배사조,변계흠청,미견명현 시망막출혈、삼출급혈관관벽개변；FFA현시병조구역강형광,만기형광소삼루.4지안시망막전견대편회백색증식막；4지안계발시망막탈리.결론 CMV성시망막염주요표현위진행성배사성적시망막염,반출혈급혈관염.
Objective To investigate the fundus characteristics and fundus fluorescence angiography (FFA) features of cytomegalovirus (CMV) retinitis associated with acquired immunodeficiency syndrome (AIDS).Methods Visual acuity,fundus features and fundus fluorescence angiography (FFA) were analyzed on 34 patients (49 eyes) with CMV retinitis.Results Representative CMV retinitis was characterized by full thickness,yellow-white,confluent granular retinal necrosis with hemorrhage,vessel sclerotic and attenuated in 29 eyes.FFA showed fluorescein leakage in late phase.Unrepresentative CMV retinitis was demonstrated in 12 eyes,recognized as granular retinal necrosis located in peripheral retina.Hemorrhage and effusion was not obvious.Pre-retina membrane was found in 4 eyes and retinal detachment in 4 eyes.Conclusions CMV refinitis has a distinctive manifestation with thickness,yellow-white retinal lesions,hemorrhage and retinal vasculitis.