CAJ | 학술논문

目的研究早产儿颅内出血的发病率,分析其影响因素.方法对2009年1月-2010年11月在东莞市妇幼保健院新生儿科住院的931例早产儿于出生3天内行头颅超声检查,并酌情于生后1周、2周、1个月时复查.同时收集相关床资料(产妇因素,产程中因素,胎儿因素,产前激素、硫酸镁应用,婴胎龄、出生体重,生后因素).结果早产儿颅脑出血发生率:931例早产儿中485例发生不同程度颅脑出血,颅脑出血总发生率为52.1%;重度出血71例(包含2例脑实质出血),发生率为7.6%.生后3天内颅内出血占总发生率92.1%,生后1周时96.1%,说明颅内出血绝大多数发生在生后1周内.证实胎龄、出生体重、生产方式、出生时窒息、常规呼吸机治疗、肺泡表面活性物质(PS)治疗、动脉血气分析pH值低等为早产儿颅内出血的高危因素.结论早产儿生后早期行颅脑超声检查对提高早产儿成活率及改善早产儿预后有重要意义.
목적 연구조산인로내출혈적발병솔,분석기영향인소.방법 대2009년1월-2010년11월재동완시부유보건원신생인과주원적931례조산인우출생3천내행두로초성검사,병작정우생후1주、2주、1개월시복사.동시수집상관상자료(산부인소,산정중인소,태인인소,산전격소、류산미응용,영태령、출생체중,생후인소).결과 조산인로뇌출혈발생솔:931례조산인중485례발생불동정도로뇌출혈,로뇌출혈총발생솔위52.1%;중도출혈71례(포함2례뇌실질출혈),발생솔위7.6%.생후3천내로내출혈점총발생솔92.1%,생후1주시96.1%,설명로내출혈절대다수발생재생후1주내.증실태령、출생체중、생산방식、출생시질식、상규호흡궤치료、폐포표면활성물질(PS)치료、동맥혈기분석pH치저등위조산인로내출혈적고위인소.결론 조산인생후조기행로뇌초성검사대제고조산인성활솔급개선조산인예후유중요의의.
Objective To study the incidence of intracranial hemorrhage in premature infants,and analyze the risk factors.Mothods 931 hospitalized premature infants that collected from the Department of Neonatology in Dongguan Matemal and Child Health Care Hospital from Jan.2009 to Nov.2010were checked with cranial uhrasonography within the first 3 days,and were reexamined by the time 1 week,2 weeks and 1 month after birth.Data regarding maternal factors,delivery characteristics,fetal risk factors,antenatal steroid administration,maternal magnesium sulfate therapy,gestational age,birth weight and neonatal parameters were collected.Results Among the 931 premature infants,485 cases(52.1%)had ICH;71 cases(7.6%)had severe ICH(including cerebral parenchymal hemorrhage 2 cases).It was confirmed that gestational age,birth weight,mode of delivery,asphyxia,mechanical ventilation,surfactant therapy,and low blood pH were risk factors of intracranial hemorrhage in premature infants.Conclusion It is useful to examine premature infant with color ultrasound on skull in early life;it helps to diagnose ICH early;and it's useful to improve the prognosis of premature infants.