CAJ | 학술논문

目的探讨脂联素与2型糖尿病大血管病变的相关性.方法 83例2型糖尿病(T2DM)患者,按有无大血管病变分为大血管病变组(43例)和无大血管病变组(40例),另设健康对照组41例,均检测血浆脂联素水平及糖化血红蛋白(HbAlc)、空腹血糖及胰岛素水平等.结果大血管病变组和无大血管病变组血浆脂联素水平明显低于正常对照组(P<0.01);大血管病变组血浆脂联素水平也明显低于无大血管病变组(P<0.01).结论血浆脂联素水平降低是T2DM和T2DM大血管病变的危险因子.
목적 탐토지련소여2형당뇨병대혈관병변적상관성.방법 83례2형당뇨병(T2DM)환자,안유무대혈관병변분위대혈관병변조(43례)화무대혈관병변조(40례),령설건강대조조41례,균검측혈장지련소수평급당화혈홍단백(HbAlc)、공복혈당급이도소수평등.결과 대혈관병변조화무대혈관병변조혈장지련소수평명현저우정상대조조(P<0.01);대혈관병변조혈장지련소수평야명현저우무대혈관병변조(P<0.01).결론 혈장지련소수평강저시T2DM화T2DM대혈관병변적위험인자.
Objective To explore the association of adiponectin and macrovascular complica-tions in patients with type 2 diabetes mellitus. Methods Eighty - three cases of type 2 diabetes mellitus were divided into two groups (43 cases with macrovascular disease and 40 cases DM without macroangi-opathy), plasma adiponectin, HbAlc, fasting plasma glucose and plasma insulin levels were detected in all cases and were compared with those of 41 healthy people. Results Adiponectin in macroangiopathy group and DM group without macroangiopathy were significantly lower than those of healthy control group (P < 0.01). Adiponectin was also significantly decreased in DM group with macroangiopathy as com-pared with DM group without macroangiopathy (P < 0.01). Conclusions The decreased adiponectin seems to be a risk factor of type 2 diabetes and its macrovascular complication.