CAJ | 학술논문

目的：观察评价舒芬太尼复合地佐辛用于癌痛患者的镇痛效果。方法：将30例适宜使用阿片类药物，自愿接受镇痛泵治疗的晚期癌痛患者随机分为两组，Ⅰ组使用舒芬太尼加托烷司琼，Ⅱ组使用舒芬太尼加地佐辛加托烷司琼。两组患者均行深静脉置管接微量输注泵自控镇痛，观察记录各时段的镇痛及镇静效果、镇痛药液用量、按压追加次数，对镇静程度、舒适程度、恶心、呕吐、呼吸抑制及全身状况进行评估。结果：两组患者追加药物按压次数比较，差异无统计学意义。恶心、呕吐发生率Ⅰ组71％，Ⅱ组4％。两组均无呼吸抑制发生。两组镇痛药液用量、镇痛效果、不良反应比较，差异均有统计学意义。结论：舒芬太尼复合地佐辛可使晚期癌痛患者获得较满意镇痛效果，大大提高了癌痛患者的生存质量。
목적：관찰평개서분태니복합지좌신용우암통환자적진통효과。방법：장30례괄의사용아편류약물，자원접수진통빙치료적만기암통환자수궤분위량조，Ⅰ조사용서분태니가탁완사경，Ⅱ조사용서분태니가지좌신가탁완사경。량조환자균행심정맥치관접미량수주빙자공진통，관찰기록각시단적진통급진정효과、진통약액용량、안압추가차수，대진정정도、서괄정도、악심、구토、호흡억제급전신상황진행평고。결과：량조환자추가약물안압차수비교，차이무통계학의의。악심、구토발생솔Ⅰ조71％，Ⅱ조4％。량조균무호흡억제발생。량조진통약액용량、진통효과、불량반응비교，차이균유통계학의의。결론：서분태니복합지좌신가사만기암통환자획득교만의진통효과，대대제고료암통환자적생존질량。
Objective:To observe and evaluate the analgesic effect of patient controlled sufentanil and dezocine intrave-nous to cancer pain. Methods:Thirty patients with cancer pain were divided into two groups:sufentanil and tropisetron group (groupⅠ)and sufentanil and tropisetron plus dezocine group(groupⅡ). Two groups of patients were both received patient controlled intravenous analgesia treatment,to observe and record the analgesic effect in each time,the pressing times and cases of adverse reactions such as respiratory depression,nausea and vomiting occur. Results:The pressing times of two groups have no statistical significance. The incidence of nausea and vomiting was 71% in groupⅠ,and 4% in groupⅡ. There were no re-spiratory depressions between two groups. Conclusion:Sufentanil combined with dezocine for patient controlled intravenous an-algesia to cancer pain can gain satisfactory effection,and improve greatly the survival quality of patients with cancer pain.