中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2008年
33期
6-8
,共3页
婴儿,新生%血液凝同%胃%肠
嬰兒,新生%血液凝同%胃%腸
영인,신생%혈액응동%위%장
Infant,newborn%Blood coagulation%Stomach%Intestines
目的 探讨胃肠功能障碍新生儿凝血功能的变化及其临床意义.方法 研究组为40例胃肠功能障碍足月新生儿,按胃肠功能障碍诊断标准分为早、中、晚期三组,分别为12、19、9例.行血常规和凝血功能检查,并进行危重病例评分.同期纳入40例正常新生儿作为对照组.比较各组间凝血功能指标的差异,并评价胃肠功能障碍与危重病例评分的关系.结果 早期组凝血功能指标与对照组比较差异无统计学意义(P>0.05),中、晚期组与对照组比较差异有统计学意义(P<0.05):中期组与晚期组凝血功能指标比较差异亦有统计学意义(P<0.05);危重病例评分越低,胃肠功能障碍程度越重.结论 胃肠功能障碍的程度越重,凝血功能紊乱程度越重,危重病例评分越低.提示一旦发生胃肠功能障碍应提高警惕,密切监测凝血功能,做好早期干预.
目的 探討胃腸功能障礙新生兒凝血功能的變化及其臨床意義.方法 研究組為40例胃腸功能障礙足月新生兒,按胃腸功能障礙診斷標準分為早、中、晚期三組,分彆為12、19、9例.行血常規和凝血功能檢查,併進行危重病例評分.同期納入40例正常新生兒作為對照組.比較各組間凝血功能指標的差異,併評價胃腸功能障礙與危重病例評分的關繫.結果 早期組凝血功能指標與對照組比較差異無統計學意義(P>0.05),中、晚期組與對照組比較差異有統計學意義(P<0.05):中期組與晚期組凝血功能指標比較差異亦有統計學意義(P<0.05);危重病例評分越低,胃腸功能障礙程度越重.結論 胃腸功能障礙的程度越重,凝血功能紊亂程度越重,危重病例評分越低.提示一旦髮生胃腸功能障礙應提高警惕,密切鑑測凝血功能,做好早期榦預.
목적 탐토위장공능장애신생인응혈공능적변화급기림상의의.방법 연구조위40례위장공능장애족월신생인,안위장공능장애진단표준분위조、중、만기삼조,분별위12、19、9례.행혈상규화응혈공능검사,병진행위중병례평분.동기납입40례정상신생인작위대조조.비교각조간응혈공능지표적차이,병평개위장공능장애여위중병례평분적관계.결과 조기조응혈공능지표여대조조비교차이무통계학의의(P>0.05),중、만기조여대조조비교차이유통계학의의(P<0.05):중기조여만기조응혈공능지표비교차이역유통계학의의(P<0.05);위중병례평분월저,위장공능장애정도월중.결론 위장공능장애적정도월중,응혈공능문란정도월중,위중병례평분월저.제시일단발생위장공능장애응제고경척,밀절감측응혈공능,주호조기간예.
Objective To investigate the changes of coagulation function in the neonates patients with gastrointestinal dysfunction and chnical significance. Methods Forty neonates with gastrointestinal dysfunction were included, which were divided into three groups according to diagnosis criterion of gastrointestinal dysfunction: early group, medium group and late group. Coagulation function was tested and neonatal critical illness score(NCIS) was done. Forty normal neonates were selected as control group. The difference of coagulation function among all groups was observed, and the relationship between coagulation function and NCIS were evaluated. Results Compared with control group, the indexs of coagulation function of early group was no statistical difference (P>0.05), however the result between medium group and late group was significantly difference (P<0.05). The difference of coagulation function between medium group and late group was also significant (P<0.05), the lower NCIS was, the more serious the gastrointestinal function was. Conclusions The more serious the gastrointestinal dysfunction is, the poorer the coagulation function is and the lower the NCIS is, which suggest coagulation function should be monitored in neonates with gastrointestinal dysfunction, and early intervention should be done accordingly.