CAJ | 학술논문

目的运用组织多普勒成像 (TDI)技术对急性心肌缺血区域和二尖瓣环侧壁处的运动速度、移动振幅进行检测，探讨TDI技术在急性心肌缺血、心肌梗死中的应用价值。方法 10只开胸猪结扎左冠状动脉前降支(LAD),通过TDI技术速度模式检测缺血区域和心尖四腔观二尖瓣环侧壁处的色泽变化及收缩、舒张期运动速度(VS,VE,VA)、移动振幅(MD,MDe,MDa)、等容收缩期时间,并与基础状态对照分析。结果 LAD结扎后，缺血区域和二尖瓣环处色泽暗淡，局部心肌色彩缺失。结扎15 s时收缩期、舒张早期运动速度、移动振幅显著降低，等容收缩期时间延长。结论 TDI技术能准确反映缺血梗死区域运动异常，精确测定局部收缩、舒张期运动速度、移动振幅，尤其二尖瓣环处的运动能反映整体心肌的运动,为临床早期评价局部心肌缺血及心功能异常提供了一种无创性的检查手段。
목적운용조직다보륵성상 (TDI)기술대급성심기결혈구역화이첨판배측벽처적운동속도、이동진폭진행검측，탐토TDI기술재급성심기결혈、심기경사중적응용개치。방법 10지개흉저결찰좌관상동맥전강지(LAD),통과TDI기술속도모식검측결혈구역화심첨사강관이첨판배측벽처적색택변화급수축、서장기운동속도(VS,VE,VA)、이동진폭(MD,MDe,MDa)、등용수축기시간,병여기출상태대조분석。결과 LAD결찰후，결혈구역화이첨판배처색택암담，국부심기색채결실。결찰15 s시수축기、서장조기운동속도、이동진폭현저강저，등용수축기시간연장。결론 TDI기술능준학반영결혈경사구역운동이상，정학측정국부수축、서장기운동속도、이동진폭，우기이첨판배처적운동능반영정체심기적운동,위림상조기평개국부심기결혈급심공능이상제공료일충무창성적검사수단。
Objective　To determine the motion velocity and mobile amplitude of acute myocardial ischemia(AMI), myocardial infarcted region and lateral wall of mitral annular using tissue Doppler imaging (TDI) and to study the available value of TDI on AMI and myocardial infarction.Methods　Ligated descending anterior branch of left coronary artery(LAD) of 10 open-chest pigs, determined the color changes of ischemia region and view mitral annular apital four-chamber lateral wall and measwred the systotic and diastotic motion velocities (VS, VE, VA), displacement (MD, MDe, MDa) and isometric contraction time interval, and compared them with that of basal states.Results　The colors of ischemia region and mitral annular were faint, local myocardial color lost after ligatured LAD. After having ligated for 15 s, the systolic and diastolic early motion velocities and mobile amplitude were decreased, time of isometric contraction was prolonged.Conclusions　TDI can accurately reflect ischemia, infarcted regional motion abnormality, accurately determine local systolic and diastolic motion velocities and displacement. Especially, the motion of mitral annular can reflect the total myocardial motion. It provides a non-invasive method for clinical to early evaluate local myocardial ischemia and abnormal myocardial function.