广东化工
廣東化工
엄동화공
GUANGDONG CHEMICAL INDUSTRY
2011年
10期
48-49
,共2页
L-乳酸酯%催化剂%酯化反应
L-乳痠酯%催化劑%酯化反應
L-유산지%최화제%지화반응
L-lactate%Catalyst%Esterification
以L-乳酸和2-异亚丙基氨基氧基乙醇为原料,经酯化反应合成了L-乳酸[（2-异亚丙基氨基氧基）乙基]酯。实验主要考察了催化剂、带水剂、反应时间、原料配比、催化剂用量等因素的影响,获得了优化的反应条件,L-乳酸酯产率可达83.2%,精酯收率78.5%,产品化学纯度98.5%,ee值99.3%。
以L-乳痠和2-異亞丙基氨基氧基乙醇為原料,經酯化反應閤成瞭L-乳痠[（2-異亞丙基氨基氧基）乙基]酯。實驗主要攷察瞭催化劑、帶水劑、反應時間、原料配比、催化劑用量等因素的影響,穫得瞭優化的反應條件,L-乳痠酯產率可達83.2%,精酯收率78.5%,產品化學純度98.5%,ee值99.3%。
이L-유산화2-이아병기안기양기을순위원료,경지화반응합성료L-유산[（2-이아병기안기양기）을기]지。실험주요고찰료최화제、대수제、반응시간、원료배비、최화제용량등인소적영향,획득료우화적반응조건,L-유산지산솔가체83.2%,정지수솔78.5%,산품화학순도98.5%,ee치99.3%。
With L-lactic acid and 2-[（isopropylidieneamino）oxy]ethanol,L-lactic acid was esterified to give 2-[（isopropylidieneamino）oxy]ethyl-L-lactate.We processed the conditional test of catalyst,water-taken reagent,reaction time,molar ratio to reactants,catalyst usage and explored a best technical condition,the yield of 2-[（isopropylidieneamino）oxy]ethyl-L-lactate was 83.2 %,the yield of refined ester was 73.2 %～78.5 %,and chemical purity,ee of production was 98.5 %,99.3 %.
