CAJ | 학술논문

对铜催化的C-N交叉偶联反应的最新研究进展作了综述.按照反应中含氮化合物种类的不同将亲核试剂分为氨基酸、胺、酰胺、含氮芳香杂环化合物、其它含氮化合物五类,对各类亲核试剂参与反应的体系(包括亲电试剂、催化剂前驱体、配体、溶剂、温度、碱、反应时间)做了全面归纳,在此基础上以配体为主线对各类亲核试剂涉及的反应进一步做了详细介绍.另外,对这一反应的机理研究也做了综述.
대동최화적C-N교차우련반응적최신연구진전작료종술.안조반응중함담화합물충류적불동장친핵시제분위안기산、알、선알、함담방향잡배화합물、기타함담화합물오류,대각류친핵시제삼여반응적체계(포괄친전시제、최화제전구체、배체、용제、온도、감、반응시간)주료전면귀납,재차기출상이배체위주선대각류친핵시제섭급적반응진일보주료상세개소.령외,대저일반응적궤리연구야주료종술.
The recent progress in copper-catalyzed C-N cross-coupling reactions is reviewed. According to the different compounds containing nitrogen, the nucleophiles are divied into the following five categories: amino acids, amines, amides, aromatic nitrogen heterocycles and others nitrogenous compounds. The reac-tion systems, in which the reaction of various types of nucleophiles were carried out, including electrophile, catalyst precusor, iigand, solvent, temperature, base and reaction time, are summarized comprehensively. Based on the ligands the above rections are described in detail. Furthermore, the studies on the mechanism of these reactions are surveyed.