CAJ | 학술논문

　　目的探讨缬沙坦在治疗心血管疾病方面的临床疗效。方法选取2010年1月-2011年1月期间收治的心血管患者120例，随机分为观察组和对照组，对照组给予常规临床治疗，观察组在常规治疗基础上给予缬沙坦口服治疗，比较两组患者的临床疗效情况。结果两组患者舒张压、收缩压均明显下降，并均达到理想水平，两组患者的治疗后舒张压、收缩压之间也没有显著性差异，P>0.05。观察组治疗后随访，共发生心血管事件2例，发生率为3.33%；对照组治疗后随访，共发生心血管事件10例，发生率为16.67%。观察组的心血管事件发生率明显低于对照组，并具有显著性差异，(χ2=34.23，P<0.05)，有统计学意义。结论心血管患者在常规治疗的基础上联合缬沙坦治疗，可以更好的舒张血管，提高对心血管的保护作用，进一步提高临床疗效，值得临床推广使用。
　　목적탐토힐사탄재치료심혈관질병방면적림상료효。방법선취2010년1월-2011년1월기간수치적심혈관환자120례，수궤분위관찰조화대조조，대조조급여상규림상치료，관찰조재상규치료기출상급여힐사탄구복치료，비교량조환자적림상료효정황。결과량조환자서장압、수축압균명현하강，병균체도이상수평，량조환자적치료후서장압、수축압지간야몰유현저성차이，P>0.05。관찰조치료후수방，공발생심혈관사건2례，발생솔위3.33%；대조조치료후수방，공발생심혈관사건10례，발생솔위16.67%。관찰조적심혈관사건발생솔명현저우대조조，병구유현저성차이，(χ2=34.23，P<0.05)，유통계학의의。결론심혈관환자재상규치료적기출상연합힐사탄치료，가이경호적서장혈관，제고대심혈관적보호작용，진일보제고림상료효，치득림상추엄사용。
Objective To investigate the clinical effcacy of Valsartan in treatment of cardiovascular diseases. Methods The hospital from January 2010 to January 2011 cardiovascular patients treated 120 cases were randomly divided into observation group and control group, the control group received routine clinical observation group was given Valsartan on the basis of conventional therapy oral treatment, the clinical effcacy of the two groups were compared. Results The two groups of patients with diastolic blood pressure, systolic blood pressure were signifcantly decreased, and to achieve the desired level of diastolic blood pressure in the two groups of patients after treatment, there was no signifcant difference between the systolic blood pressure (P>0.05). After treatment, follow-up, two cases of cardiovascular events, incidence of 3.33%; control group after treatment follow-up, a total of 10 cases of cardiovascular events, the rate was 16.67%. Observation group, the incidence of cardiovascular events was signifcantly lower than the control group, with a signifcant difference (χ2= 34.23,P<0.05) was statistically signifcant. Conclusion Patients with cardiovascular disease on the basis of conventional therapy combined with Valsartan in the treatment, can better relaxing blood vessels, improve the protective effect on cardiovascular system, further improve clinical effcacy, is worthy of clinical use.