广东药学院学报
廣東藥學院學報
엄동약학원학보
ACADEMIC JOURNAL OF GUANGDONG COLLEGE OF PHARMACY
2001年
2期
89-90
,共2页
复方氨酚烷胺胶囊%对乙酰氨基酚%溶出度
複方氨酚烷胺膠囊%對乙酰氨基酚%溶齣度
복방안분완알효낭%대을선안기분%용출도
目的：建立复方氨酚烷胺胶囊溶出度的测定方法。方法：转篮法，采用ODS柱，流动相为V(甲醇)∶V（0.05 mol/L磷酸二氢钾）=100∶400，检测波长为254 nm。结果：对乙酰氨基酚的线性范围为0.1108～0.7756 μg，回收率为100.7%(RSD=0.50%)。结论：本方法结果准确，可作为该品种溶出度测定的检测方法。
目的：建立複方氨酚烷胺膠囊溶齣度的測定方法。方法：轉籃法，採用ODS柱，流動相為V(甲醇)∶V（0.05 mol/L燐痠二氫鉀）=100∶400，檢測波長為254 nm。結果：對乙酰氨基酚的線性範圍為0.1108～0.7756 μg，迴收率為100.7%(RSD=0.50%)。結論：本方法結果準確，可作為該品種溶齣度測定的檢測方法。
목적：건립복방안분완알효낭용출도적측정방법。방법：전람법，채용ODS주，류동상위V(갑순)∶V（0.05 mol/L린산이경갑）=100∶400，검측파장위254 nm。결과：대을선안기분적선성범위위0.1108～0.7756 μg，회수솔위100.7%(RSD=0.50%)。결론：본방법결과준학，가작위해품충용출도측정적검측방법。
Objective：To establish a HPLC method for the determination of the dissolution of Compound Paracetamol and Amantadine Hydrochloride Capsules. Method： A basket stirring method was applied. ODS column was used ，with the mobile phase of 0.05 mol/L KH2PO4-methanol(40∶10) and detective wavelength of 254 nm. Results：The linear range of paracetamol was 0.1108～0.7756 μg.The average recovery (n=5) was 100.7% (RSD=0.50%). Conclusion：The method is accurate and suitable for the determination of the dissolution of Compound Paracetamoland Amantadine Hydrochloride Capsules.
