CAJ | 학술논문

目的：了解小肝癌和肝转移癌行经皮乙酸注射(简称PAI)的临床效果。方法：5例小肝癌、3例肝转移癌在CT引导下经皮乙酸注射化学灭活术。结果：在8例中，除3例在注射时有明显腹痛外，没有其他的临床并发症。随访2～7个月，7例病人的肿瘤病变成为低密度至囊状改变，1例于PAI后1周行部分肝切除术，病检示肿瘤全部坏死。结论：初步结果表明，在小肝癌和1至3个小病灶的肝转移癌中PAI是有效的，它有可能取代部分肝癌切除术。
목적：료해소간암화간전이암행경피을산주사(간칭PAI)적림상효과。방법：5례소간암、3례간전이암재CT인도하경피을산주사화학멸활술。결과：재8례중，제3례재주사시유명현복통외，몰유기타적림상병발증。수방2～7개월，7례병인적종류병변성위저밀도지낭상개변，1례우PAI후1주행부분간절제술，병검시종류전부배사。결론：초보결과표명，재소간암화1지3개소병조적간전이암중PAI시유효적，타유가능취대부분간암절제술。
Objective:To assess the clinical efficacy of CT-guidedpercutaneous acetic acid injection(PAI) for chemo-ablation of hepatic neoplasms.Methods:5 small hepatocellular carcinomas(HCCs) and 3 hepatic metastatic carcinomas(HMCs) were performed chemo-ablation of PAI under the CT-guidance.Results:Results of the preliminary study of PAI showed that no clinically significant complications occurred except remarkable abdominal pain in 3 of 8 PAIs.7 lesions became less dense to cystic after2～7months of CT follow-up.One patient was performed surgical partial hepatic resection,there was no neoplastic cell in the lesion unless a complete necrosis of tumor.Conclusion:The initial results of PAI suggest that chemo-ablation of small HCCs and small 1～3 foci of HMCs may prove to be an effective method.It is promising that PAI will take the place of partial hepatic resection for treatment of small HCCs and other hepatic neoplasms.