CAJ | 학술논문

目的探讨特种功能精细陶瓷对“血瘀证”兔血红细胞变形性的影响及机理。方法用激光衍射仪测定0～1000s－1切变率下兔红细胞变形性DI－R曲线和应力松弛DI－T曲线，观察红细胞力学特性；采用荧光分光光度计测量经特种功能精细陶瓷温育后兔血液的荧光偏振度，观察其红细胞膜流动性。结果与对照组相比，在特种功能精细陶瓷作用下，兔红细胞变形性得到明显提高(P<0.001),红细胞膜流动性明显改善(P<0.001)。结论特种功能精细陶瓷可增加“血瘀证”兔血红细胞变形性，其机理是增加细胞膜的力学特性、粘弹性和膜流动性。
목적탐토특충공능정세도자대“혈어증”토혈홍세포변형성적영향급궤리。방법용격광연사의측정0～1000s－1절변솔하토홍세포변형성DI－R곡선화응력송이DI－T곡선，관찰홍세포역학특성；채용형광분광광도계측량경특충공능정세도자온육후토혈액적형광편진도，관찰기홍세포막류동성。결과여대조조상비，재특충공능정세도자작용하，토홍세포변형성득도명현제고(P<0.001),홍세포막류동성명현개선(P<0.001)。결론특충공능정세도자가증가“혈어증”토혈홍세포변형성，기궤리시증가세포막적역학특성、점탄성화막류동성。
Objectve To observe the effect of functional fine ceramics (FFC) on blood stasis rabbits' erythrocytic deformability and inquire into its mechanism. Methods To observe the change of erythrocytic mechanical property, Laser Diffractive Analyzer was used to test the rabbits' erthrocytic deformability DI_R curve, and stress relaxation, DI_T curve during the shear rate of 0－ 1000S－ 1. Furthermore, to observe the erythrocytic membranous fluidity. Fluorescent Spectrometer was used to test the degree of fluorescent polarization of rabbits' blood warm_cultivated with the FFC powder. Results The FFC could enhance the erthrocytic deformability and improve the membranous fluidity, compared with the control group, the differences were significant (P<0.001). Conclusion The FFC could promote blood stasis rabbits' erythrocytic deformability, its mechanism is the increase of erythrocytic mechanical property, viscoelasticity and membranous fluidity.